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Multiomic analysis reveals cellular and epigenetic plasticity in intestinal pouches of ulcerative colitis patients

BACKGROUND & AIMS: Total proctocolectomy with ileal pouch anal anastomosis (IPAA) is the standard of care for patients with severe treatment resistant ulcerative colitis (UC). Despite improvements in patient outcomes, about 50% of patients will develop inflammation of the pouch within 1–2 years...

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Detalles Bibliográficos
Autores principales:	Zhao, Yu, Zhou, Ran, Xie, Bingqing, Liu, Cambrian Y, Kalski, Martin, Cham, Candace M, Koval, Jason, Weber, Christopher R, Rubin, David T, Sogin, Mitch, Crosson, Sean, Huang, Jun, Fiebig, Aretha, Dalal, Sushila, Chang, Eugene B, Basu, Anindita, Pott, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680893/ https://www.ncbi.nlm.nih.gov/pubmed/38014192 http://dx.doi.org/10.1101/2023.11.11.23298309

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