The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer

The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen‐presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune response to...

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Detalles Bibliográficos
Autores principales: Wang, Shuangcui, Zhang, Guan, Cui, Qian, Yang, Yanjie, Wang, Dong, Liu, Aqing, Xia, Ying, Li, Wentao, Liu, Yunhe, Yu, Jianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681037/
https://www.ncbi.nlm.nih.gov/pubmed/38018578
http://dx.doi.org/10.1002/iid3.1099
Descripción
Sumario:The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen‐presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune response to non‐small cell lung cancer (NSCLC). In this article, a review was made of the interaction between DCs and T cells in the treatment of NSCLC and how this interaction affects the treatment outcome.

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