A novel program of infiltrative control in astrocytomas: ADAM23 depletion promotes cell invasion by activating γ-secretase complex

BACKGROUND: Infiltration is a life-threatening growth pattern in malignant astrocytomas and a significant cause of therapy resistance. It results in the tumor cell spreading deeply into the surrounding brain tissue, fostering tumor recurrence and making complete surgical resection impossible. We nee...

Descripción completa

Detalles Bibliográficos
Autores principales: Jandrey, Elisa Helena Farias, Barnabé, Gabriela Filoso, Maldaun, Marcos, Asprino, Paula Fontes, dos Santos, Natália Cristina, Inoue, Lilian Tiemi, Rozanski, Andrei, Galante, Pedro Alexandre Favoretto, Marie, Suely Kazue Nagahashi, Oba-Shinjo, Sueli Mieko, dos Santos, Tiago Góss, Chammas, Roger, Lancellotti, Carmen Lucia Penteado, Furnari, Frank B, Camargo, Anamaria Aranha, Costa, Érico Tosoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681280/
https://www.ncbi.nlm.nih.gov/pubmed/38024245
http://dx.doi.org/10.1093/noajnl/vdad147

Ejemplares similares

Ejemplares similares