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Leishmanicidal and healing effects of 3β,6β,16β-trihydroxy lup-20 (29)-ene isolated from Combretum leprosum on Leishmania braziliensis infection in vitro and in vivo

Treatment of cutaneous leishmaniasis depends on drugs that potentially cause serious side effects and resistance. Thus, topical therapies are attractive alternatives to the drugs currently used. 3β, 6β, 16β-trihydroxylup-20 (29)-ene is a lupane triterpene isolated from Combretum leprosum Mart. leave...

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Detalles Bibliográficos
Autores principales:	Sombra Santos, Aline, de Castro Rodrigues, Naya Lúcia, Marciano Fonseca, Francisco Rafael, Braga Fayão Oliveira, Nathalia, Oliveira Loucard, Bianca, Fernandes Heredia, Fabíola, Albuquerque Gomes Nogueira, Teresa Neuma, Monteiro Abreu, Ticiana, Silva dos Santos, Hélcio, Holanda Teixeira, Edson, Almeida Moreira Leal, Luzia Kalyne, Brandim Gomes, Regis Bernardo, Romero Teixeira, Clarissa, Teixeira, Maria Jania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681296/ https://www.ncbi.nlm.nih.gov/pubmed/38011211 http://dx.doi.org/10.1371/journal.pone.0287665

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