MIWI N-terminal RG motif promotes efficient pachytene piRNA production and spermatogenesis independent of LINE1 transposon silencing

PIWI proteins and their associated piRNAs act to silence transposons and promote gametogenesis. Murine PIWI proteins MIWI, MILI, and MIWI2 have multiple arginine and glycine (RG)-rich motifs at their N-terminal domains. Despite being known as docking sites for the TDRD family proteins, the in vivo r...

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Detalles Bibliográficos
Autores principales: Wei, Chao, Jing, Jiongjie, Yan, Xiaoyuan, Mann, Jeffrey M., Geng, Ruirong, Xie, Huirong, Demireva, Elena Y., Hess, Rex A., Ding, Deqiang, Chen, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681313/
https://www.ncbi.nlm.nih.gov/pubmed/37956204
http://dx.doi.org/10.1371/journal.pgen.1011031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681313/
https://www.ncbi.nlm.nih.gov/pubmed/37956204
http://dx.doi.org/10.1371/journal.pgen.1011031

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