Cargando…
The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study
BACKGROUND: Among the complications related to chronic kidney disease (CKD), those of a neurological nature stand out, and for a better quality of life for patients, the diagnosis and treatment of these complications is fundamental. OBJECTIVES: This study aimed to assess the effect of hemodialysis o...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Paulista de Medicina - APM
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681329/ https://www.ncbi.nlm.nih.gov/pubmed/38018633 http://dx.doi.org/10.1590/1516-3180.2023.0068.R1.07072023 |
_version_ | 1785150793944399872 |
---|---|
author | Koch, Mariana Schechtel Drewnowski, Bianca Rickli, Cristiane dos Santos, Fábio André Baroni, Gilberto Vellosa, José Carlos Rebuglio |
author_facet | Koch, Mariana Schechtel Drewnowski, Bianca Rickli, Cristiane dos Santos, Fábio André Baroni, Gilberto Vellosa, José Carlos Rebuglio |
author_sort | Koch, Mariana Schechtel |
collection | PubMed |
description | BACKGROUND: Among the complications related to chronic kidney disease (CKD), those of a neurological nature stand out, and for a better quality of life for patients, the diagnosis and treatment of these complications is fundamental. OBJECTIVES: This study aimed to assess the effect of hemodialysis on intracranial pressure waveform (ICPw) in patients with chronic kidney disease undergoing hemodialysis and those who are not yet undergoing substitutive therapy. DESIGN AND SETTING: An observational study was conducted in two stages at a kidney replacement therapy center in Brazil. The first was a longitudinal study and the second was a cross-sectional study. METHODS: Forty-two patients on hemodialysis were included in the first stage of the study. In the second stage, 226 participants were included. Of these, 186 were individuals with chronic kidney disease (who were not undergoing substitutive therapy), and 40 did not have the disease (control group). The participants’ intracranial compliance was assessed using the non-invasive Brain4care method, and the results were compared between the groups. RESULTS: There was a significant difference between the hemodialysis and non-hemodialysis groups, with the former having better ICPw conditions. CONCLUSIONS: Hemodialysis influenced the improvement in ICPw, probably due to the decrease in the patients’ extra-and intracellular volumes. Furthermore, ICPw monitoring can be a new parameter to consider when defining the moment to start substitutive therapy. |
format | Online Article Text |
id | pubmed-10681329 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Associação Paulista de Medicina - APM |
record_format | MEDLINE/PubMed |
spelling | pubmed-106813292023-11-27 The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study Koch, Mariana Schechtel Drewnowski, Bianca Rickli, Cristiane dos Santos, Fábio André Baroni, Gilberto Vellosa, José Carlos Rebuglio Sao Paulo Med J Original Article BACKGROUND: Among the complications related to chronic kidney disease (CKD), those of a neurological nature stand out, and for a better quality of life for patients, the diagnosis and treatment of these complications is fundamental. OBJECTIVES: This study aimed to assess the effect of hemodialysis on intracranial pressure waveform (ICPw) in patients with chronic kidney disease undergoing hemodialysis and those who are not yet undergoing substitutive therapy. DESIGN AND SETTING: An observational study was conducted in two stages at a kidney replacement therapy center in Brazil. The first was a longitudinal study and the second was a cross-sectional study. METHODS: Forty-two patients on hemodialysis were included in the first stage of the study. In the second stage, 226 participants were included. Of these, 186 were individuals with chronic kidney disease (who were not undergoing substitutive therapy), and 40 did not have the disease (control group). The participants’ intracranial compliance was assessed using the non-invasive Brain4care method, and the results were compared between the groups. RESULTS: There was a significant difference between the hemodialysis and non-hemodialysis groups, with the former having better ICPw conditions. CONCLUSIONS: Hemodialysis influenced the improvement in ICPw, probably due to the decrease in the patients’ extra-and intracellular volumes. Furthermore, ICPw monitoring can be a new parameter to consider when defining the moment to start substitutive therapy. Associação Paulista de Medicina - APM 2023-11-27 /pmc/articles/PMC10681329/ /pubmed/38018633 http://dx.doi.org/10.1590/1516-3180.2023.0068.R1.07072023 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article Koch, Mariana Schechtel Drewnowski, Bianca Rickli, Cristiane dos Santos, Fábio André Baroni, Gilberto Vellosa, José Carlos Rebuglio The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study |
title | The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study |
title_full | The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study |
title_fullStr | The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study |
title_full_unstemmed | The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study |
title_short | The influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study |
title_sort | influence of hemodialysis on intracranial pressure waveform in patients with chronic kidney disease: an observational study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681329/ https://www.ncbi.nlm.nih.gov/pubmed/38018633 http://dx.doi.org/10.1590/1516-3180.2023.0068.R1.07072023 |
work_keys_str_mv | AT kochmarianaschechtel theinfluenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT drewnowskibianca theinfluenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT ricklicristiane theinfluenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT dossantosfabioandre theinfluenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT baronigilberto theinfluenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT vellosajosecarlosrebuglio theinfluenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT kochmarianaschechtel influenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT drewnowskibianca influenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT ricklicristiane influenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT dossantosfabioandre influenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT baronigilberto influenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy AT vellosajosecarlosrebuglio influenceofhemodialysisonintracranialpressurewaveforminpatientswithchronickidneydiseaseanobservationalstudy |