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Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis

In a meta‐analysis, we assessed the impact of different surgical approaches on the outcome of hepatectomy with hepatocellular carcinoma. Four databases, including PubMed, Embase, Cochrane Library, and the Web of Science, have been critically reviewed through the full literature through June 2023. El...

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Autores principales: Zhang, Junli, Shi, Meiping, Ding, Wan, Duan, Mingda, Dai, Ziqing, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681463/
https://www.ncbi.nlm.nih.gov/pubmed/37442783
http://dx.doi.org/10.1111/iwj.14313
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author Zhang, Junli
Shi, Meiping
Ding, Wan
Duan, Mingda
Dai, Ziqing
Chen, Yu
author_facet Zhang, Junli
Shi, Meiping
Ding, Wan
Duan, Mingda
Dai, Ziqing
Chen, Yu
author_sort Zhang, Junli
collection PubMed
description In a meta‐analysis, we assessed the impact of different surgical approaches on the outcome of hepatectomy with hepatocellular carcinoma. Four databases, including PubMed, Embase, Cochrane Library, and the Web of Science, have been critically reviewed through the full literature through June 2023. Eleven related trials were examined once they had met the trial's classification and exclusion criteria, as well as the assessment of the quality. A random effects approach was applied to analysis of operative organ infections, and a fixed‐effect model was applied to determine the 95% CI and OR. Analysis of the data was done with RevMan 5.3. Our findings indicated that patients undergoing minimally invasive liver cancer surgery had significantly lower risks of surgical organ infection (OR, 0.35; 95% CI, 0.16–0.77; p = 0.009) and wound infection (OR, 0.19; 95% CI, 0.13–0.28; p < 0.001) compared to those undergoing open surgery. There was no heterogeneity observed between the two groups (I (2) = 0) in wound infection. Nevertheless, because of the limited number of randomised controlled trials in this meta‐analysis, care should be taken and carefully considered in the treatment of these values. Further high‐quality studies involving a large number of samples are needed to validate and reinforce the results.
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spelling pubmed-106814632023-07-13 Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis Zhang, Junli Shi, Meiping Ding, Wan Duan, Mingda Dai, Ziqing Chen, Yu Int Wound J Original Articles In a meta‐analysis, we assessed the impact of different surgical approaches on the outcome of hepatectomy with hepatocellular carcinoma. Four databases, including PubMed, Embase, Cochrane Library, and the Web of Science, have been critically reviewed through the full literature through June 2023. Eleven related trials were examined once they had met the trial's classification and exclusion criteria, as well as the assessment of the quality. A random effects approach was applied to analysis of operative organ infections, and a fixed‐effect model was applied to determine the 95% CI and OR. Analysis of the data was done with RevMan 5.3. Our findings indicated that patients undergoing minimally invasive liver cancer surgery had significantly lower risks of surgical organ infection (OR, 0.35; 95% CI, 0.16–0.77; p = 0.009) and wound infection (OR, 0.19; 95% CI, 0.13–0.28; p < 0.001) compared to those undergoing open surgery. There was no heterogeneity observed between the two groups (I (2) = 0) in wound infection. Nevertheless, because of the limited number of randomised controlled trials in this meta‐analysis, care should be taken and carefully considered in the treatment of these values. Further high‐quality studies involving a large number of samples are needed to validate and reinforce the results. Blackwell Publishing Ltd 2023-07-13 /pmc/articles/PMC10681463/ /pubmed/37442783 http://dx.doi.org/10.1111/iwj.14313 Text en © 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Zhang, Junli
Shi, Meiping
Ding, Wan
Duan, Mingda
Dai, Ziqing
Chen, Yu
Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis
title Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis
title_full Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis
title_fullStr Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis
title_full_unstemmed Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis
title_short Effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: A meta‐analysis
title_sort effect of minimally invasive versus open surgery in hepatectomy on postoperative wound complications in patients with hepatocellular carcinoma: a meta‐analysis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681463/
https://www.ncbi.nlm.nih.gov/pubmed/37442783
http://dx.doi.org/10.1111/iwj.14313
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