Cargando…
Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients
Pyoderma gangrenosum (PG) is a non‐infectious, neutrophilic dermatosis that was difficult to diagnose in clinical practice. Today, the PARACELSUS score is a validated tool for diagnostics. Based on this score, patients with clearly diagnosed PG were examined with regard to predilection sites. In thi...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681478/ https://www.ncbi.nlm.nih.gov/pubmed/37528508 http://dx.doi.org/10.1111/iwj.14323 |
_version_ | 1785142542786887680 |
---|---|
author | Moelleken, Maurice Erfurt‐Berge, Cornelia Ronicke, Moritz Busch, Dorothee Hübner, Ursula Hertha Hüsers, Jens Przysucha, Mareike Dissemond, Joachim |
author_facet | Moelleken, Maurice Erfurt‐Berge, Cornelia Ronicke, Moritz Busch, Dorothee Hübner, Ursula Hertha Hüsers, Jens Przysucha, Mareike Dissemond, Joachim |
author_sort | Moelleken, Maurice |
collection | PubMed |
description | Pyoderma gangrenosum (PG) is a non‐infectious, neutrophilic dermatosis that was difficult to diagnose in clinical practice. Today, the PARACELSUS score is a validated tool for diagnostics. Based on this score, patients with clearly diagnosed PG were examined with regard to predilection sites. In this retrospective study, the data of patients from the University Hospitals of Essen and Erlangen were analysed in whom the diagnosis of PG could be clearly confirmed using the PARACELSUS score. A total of 170 patients, 49 men (29%) and 121 women (71%) with an average age at first manifestation of 55.5 years, could be included in the analysis. The predilection sites were identified as the lower legs in 80.6% of the patients and the extensor sides in 75.2%. Other localisations of PG were the thighs in 14.1%, mammae and abdomen in 10.0% each, back and gluteal in 7.1% each, feet in 5.9%, arms in 4.7%, genital in 3.5% and head in 2.9%. This retrospective study is the first to identify a collective of PG patients with the highest data quality using the PARACELSUS score. It could be shown that PG can basically occur on the entire integument. However, the predilection sites of PG, which have now been reliably identified for the first time, are the lower legs and in particular the extensor sides. |
format | Online Article Text |
id | pubmed-10681478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-106814782023-08-01 Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients Moelleken, Maurice Erfurt‐Berge, Cornelia Ronicke, Moritz Busch, Dorothee Hübner, Ursula Hertha Hüsers, Jens Przysucha, Mareike Dissemond, Joachim Int Wound J Original Articles Pyoderma gangrenosum (PG) is a non‐infectious, neutrophilic dermatosis that was difficult to diagnose in clinical practice. Today, the PARACELSUS score is a validated tool for diagnostics. Based on this score, patients with clearly diagnosed PG were examined with regard to predilection sites. In this retrospective study, the data of patients from the University Hospitals of Essen and Erlangen were analysed in whom the diagnosis of PG could be clearly confirmed using the PARACELSUS score. A total of 170 patients, 49 men (29%) and 121 women (71%) with an average age at first manifestation of 55.5 years, could be included in the analysis. The predilection sites were identified as the lower legs in 80.6% of the patients and the extensor sides in 75.2%. Other localisations of PG were the thighs in 14.1%, mammae and abdomen in 10.0% each, back and gluteal in 7.1% each, feet in 5.9%, arms in 4.7%, genital in 3.5% and head in 2.9%. This retrospective study is the first to identify a collective of PG patients with the highest data quality using the PARACELSUS score. It could be shown that PG can basically occur on the entire integument. However, the predilection sites of PG, which have now been reliably identified for the first time, are the lower legs and in particular the extensor sides. Blackwell Publishing Ltd 2023-08-01 /pmc/articles/PMC10681478/ /pubmed/37528508 http://dx.doi.org/10.1111/iwj.14323 Text en © 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Moelleken, Maurice Erfurt‐Berge, Cornelia Ronicke, Moritz Busch, Dorothee Hübner, Ursula Hertha Hüsers, Jens Przysucha, Mareike Dissemond, Joachim Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients |
title | Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients |
title_full | Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients |
title_fullStr | Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients |
title_full_unstemmed | Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients |
title_short | Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients |
title_sort | predilection sites of pyoderma gangrenosum: retrospective study of 170 clearly diagnosed patients |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681478/ https://www.ncbi.nlm.nih.gov/pubmed/37528508 http://dx.doi.org/10.1111/iwj.14323 |
work_keys_str_mv | AT moellekenmaurice predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients AT erfurtbergecornelia predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients AT ronickemoritz predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients AT buschdorothee predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients AT hubnerursulahertha predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients AT husersjens predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients AT przysuchamareike predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients AT dissemondjoachim predilectionsitesofpyodermagangrenosumretrospectivestudyof170clearlydiagnosedpatients |