Cargando…

Guiding model‐driven combination dose selection using multi‐objective synergy optimization

Despite the growing appreciation that the future of cancer treatment lies in combination therapies, finding the right drugs to combine and the optimal way to combine them remains a nontrivial task. Herein, we introduce the Multi‐Objective Optimization of Combination Synergy – Dose Selection (MOOCS‐D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gevertz, Jana L., Kareva, Irina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681518/ https://www.ncbi.nlm.nih.gov/pubmed/37415306 http://dx.doi.org/10.1002/psp4.12997

Ejemplares similares

Pretomanid dose selection for pulmonary tuberculosis: An application of multi‐objective optimization to dosage regimen design
por: Lyons, Michael A.
Publicado: (2021)

Bispecific antibodies: A guide to model informed drug discovery and development
por: Kareva, Irina, et al.
Publicado: (2021)

Data-driven multi-objective optimization for electric vehicle charging infrastructure
por: Farhadi, Farzaneh, et al.
Publicado: (2023)

Computational Modeling of Tumor Response to Vascular-Targeting Therapies—Part I: Validation
por: Gevertz, Jana L.
Publicado: (2011)

SynergyFinder 2.0: visual analytics of multi-drug combination synergies
por: Ianevski, Aleksandr, et al.
Publicado: (2020)

A Combination of Immune Checkpoint Inhibition with Metronomic Chemotherapy as a Way of Targeting Therapy-Resistant Cancer Cells
por: Kareva, Irina
Publicado: (2017)

Correction to ‘SynergyFinder 2.0: visual analytics of multi-drug combination synergies’
Publicado: (2022)

Screening for Combination Cancer Therapies With Dynamic Fuzzy Modeling and Multi-Objective Optimization
por: Spolaor, Simone, et al.
Publicado: (2021)

Muscle synergy space: learning model to create an optimal muscle synergy
por: Alnajjar, Fady, et al.
Publicado: (2013)

Multi-Objective Optimization of Sugarcane Milling System Operations Based on a Deep Data-Driven Model
por: Li, Zhengyuan, et al.
Publicado: (2022)

Multi-Objective Optimization Based Multi-Bernoulli Sensor Selection for Multi-Target Tracking
por: Zhu, Yun, et al.
Publicado: (2019)

A Novel Three-Phase Model of Brain Tissue Microstructure
por: Gevertz, Jana L., et al.
Publicado: (2008)

Correction: A Novel Three-Phase Model of Brain Tissue Microstructure
por: Gevertz, Jana L., et al.
Publicado: (2009)

Leukocyte Motility Models Assessed through Simulation and Multi-objective Optimization-Based Model Selection
por: Read, Mark N., et al.
Publicado: (2016)

Additive Dose Response Models: Defining Synergy
por: Lederer, Simone, et al.
Publicado: (2019)

Optimization of Antioxidant Synergy in a Polyherbal Combination by Experimental Design
por: Mapeka, Tsholofelo M., et al.
Publicado: (2022)

Developing a Minimally Structured Mathematical Model of Cancer Treatment with Oncolytic Viruses and Dendritic Cell Injections
por: Gevertz, Jana L., et al.
Publicado: (2018)

A Riemannian Geometry Theory of Synergy Selection for Visually-Guided Movement
por: Neilson, Peter D., et al.
Publicado: (2021)

Dosage and Dose Schedule Screening of Drug Combinations in Agent-Based Models Reveals Hidden Synergies
por: Barros de Andrade e Sousa, Lisa C., et al.
Publicado: (2016)

Multi-objective optimization using evolutionary algorithms /
por: Deb, Kalyanmoy
Publicado: (2008)

Multi-objective optimization using evolutionary algorithms /
por: Deb, Kalyanmoy
Publicado: (2001)

Multi-objective optimization of coronary stent using Kriging surrogate model
por: Li, Hongxia, et al.
Publicado: (2016)

Multi-Objective Optimization of the Basic and Regenerative ORC Integrated with Working Fluid Selection
por: Zhou, Yuhao, et al.
Publicado: (2022)

Indoor Localization with Multi-objective Selection of Radiomap Models
por: Alexandrou, Rafael, et al.
Publicado: (2020)

Accelerated current-driven multi-objective topology optimization for compact ultrawide-band MIMO antenna design
por: Yuan, Xia, et al.
Publicado: (2022)

Phage-Antibiotic Synergy Is Driven by a Unique Combination of Antibacterial Mechanism of Action and Stoichiometry
por: Gu Liu, Carmen, et al.
Publicado: (2020)

Non-convex multi-objective optimization
por: Pardalos, Panos M, et al.
Publicado: (2017)

From Fitting the Average to Fitting the Individual: A Cautionary Tale for Mathematical Modelers
por: Luo, Michael C., et al.
Publicado: (2022)

MOCOVIDOA: a novel multi-objective coronavirus disease optimization algorithm for solving multi-objective optimization problems
por: Khalid, Asmaa M., et al.
Publicado: (2023)

Mathematical model of a cytokine storm
por: Kareva, Irina, et al.
Publicado: (2022)

EEG Channel-Selection Method for Epileptic-Seizure Classification Based on Multi-Objective Optimization
por: Moctezuma, Luis Alfredo, et al.
Publicado: (2020)

Pixel-Guided Association for Multi-Object Tracking
por: Boragule, Abhijeet, et al.
Publicado: (2022)

Multi-objective optimization using artificial intelligence techniques
por: Mirjalili, Seyedali, et al.
Publicado: (2019)

Prisoner's Dilemma in Cancer Metabolism
por: Kareva, Irina
Publicado: (2011)

Biological Stoichiometry in Tumor Micro-environments
por: Kareva, Irina
Publicado: (2013)

Primary and metastatic tumor dormancy as a result of population heterogeneity
por: Kareva, Irina
Publicado: (2016)

Immune Suppression in Pregnancy and Cancer: Parallels and Insights
por: Kareva, Irina
Publicado: (2020)

Understanding Metabolic Alterations in Cancer Cachexia through the Lens of Exercise Physiology
por: Kareva, Irina
Publicado: (2022)

Pharmacokinetics of caspofungin acetate to guide optimal dosing in cats
por: Leshinsky, Jana, et al.
Publicado: (2017)

A Multi-Objective Carnivorous Plant Algorithm for Solving Constrained Multi-Objective Optimization Problems
por: Yang, Yufei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i0tkj7ooa92js181m72ha5ncqm