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Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report

RATIONALE: Primary synovial sarcoma of the prostate is an extremely rare mesenchymal malignant soft tissue tumor with unique morphological features. Synovial sarcoma often occurs in the pararticular tissues of limbs in young people, but rarely occurs in prostate. Because it is very rare, it is easil...

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Autores principales: Shi, Qichong, Zhou, Yun, Wang, Longmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681603/
https://www.ncbi.nlm.nih.gov/pubmed/38013382
http://dx.doi.org/10.1097/MD.0000000000036151
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author Shi, Qichong
Zhou, Yun
Wang, Longmei
author_facet Shi, Qichong
Zhou, Yun
Wang, Longmei
author_sort Shi, Qichong
collection PubMed
description RATIONALE: Primary synovial sarcoma of the prostate is an extremely rare mesenchymal malignant soft tissue tumor with unique morphological features. Synovial sarcoma often occurs in the pararticular tissues of limbs in young people, but rarely occurs in prostate. Because it is very rare, it is easily misdiagnosed as benign prostatic hyperplasia or prostate cancer clinically. A case of synchronous acinar adenocarcinoma of the prostate has not been reported. In this article, we report a unique case of primary prostatic synovial sarcoma with acinar adenocarcinoma. PATIENT CONCERNS: A 58-year-old male patient was found to have a prostate mass during physical examination. Prostate ultrasound examination showed an increase in prostate volume of 5.2 × 3.3 × 3.3 cm, mixed echo mass can be seen on the left side of the prostate, with a size of approximately 4.9 × 4.3 cm, left seminal vesicle compressed. DIAGNOSES: Prostatic synovial sarcoma (biphasic type) combined with prostatic acinar adenocarcinoma (Gleason 3 + 3). INTERVENTION: The patient received radical prostatectomy, followed by adjuvant chemotherapy and radiotherapy. OUTCOME: After 2 months of follow-up, at the time of writing this article, the patient received a comprehensive treatment plan of adjuvant chemotherapy and radiotherapy for 2 months, and no recurrence or metastasis was found. LESSONS: Primary prostatic synovial sarcoma (biphasic type) combined with prostatic acinar adenocarcinoma is a very unique and rare case, and effective treatment guidelines are not yet clear, posing new challenges to clinical treatment. Making full use of pathological and imaging examinations, early diagnosis and radical surgery combined with multidisciplinary treatment seem to be still a positive method.
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spelling pubmed-106816032023-11-24 Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report Shi, Qichong Zhou, Yun Wang, Longmei Medicine (Baltimore) 7300 RATIONALE: Primary synovial sarcoma of the prostate is an extremely rare mesenchymal malignant soft tissue tumor with unique morphological features. Synovial sarcoma often occurs in the pararticular tissues of limbs in young people, but rarely occurs in prostate. Because it is very rare, it is easily misdiagnosed as benign prostatic hyperplasia or prostate cancer clinically. A case of synchronous acinar adenocarcinoma of the prostate has not been reported. In this article, we report a unique case of primary prostatic synovial sarcoma with acinar adenocarcinoma. PATIENT CONCERNS: A 58-year-old male patient was found to have a prostate mass during physical examination. Prostate ultrasound examination showed an increase in prostate volume of 5.2 × 3.3 × 3.3 cm, mixed echo mass can be seen on the left side of the prostate, with a size of approximately 4.9 × 4.3 cm, left seminal vesicle compressed. DIAGNOSES: Prostatic synovial sarcoma (biphasic type) combined with prostatic acinar adenocarcinoma (Gleason 3 + 3). INTERVENTION: The patient received radical prostatectomy, followed by adjuvant chemotherapy and radiotherapy. OUTCOME: After 2 months of follow-up, at the time of writing this article, the patient received a comprehensive treatment plan of adjuvant chemotherapy and radiotherapy for 2 months, and no recurrence or metastasis was found. LESSONS: Primary prostatic synovial sarcoma (biphasic type) combined with prostatic acinar adenocarcinoma is a very unique and rare case, and effective treatment guidelines are not yet clear, posing new challenges to clinical treatment. Making full use of pathological and imaging examinations, early diagnosis and radical surgery combined with multidisciplinary treatment seem to be still a positive method. Lippincott Williams & Wilkins 2023-11-24 /pmc/articles/PMC10681603/ /pubmed/38013382 http://dx.doi.org/10.1097/MD.0000000000036151 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 7300
Shi, Qichong
Zhou, Yun
Wang, Longmei
Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report
title Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report
title_full Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report
title_fullStr Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report
title_full_unstemmed Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report
title_short Primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: A case report
title_sort primary synovial sarcoma and acinar adenocarcinoma of prostate rarely occur simultaneously: a case report
topic 7300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681603/
https://www.ncbi.nlm.nih.gov/pubmed/38013382
http://dx.doi.org/10.1097/MD.0000000000036151
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