The effect of atopic dermatitis in pediatric patients on height: Reflections triggered by a real-life case report

RATIONALE: Atopic dermatitis (AD) is a burdensome skin disorder, especially in children. The prevalence of children with AD is increasing year by year in China. Typical symptoms like eczema-like lesions and severe pruritus can seriously affect the sleep quality and the growth and development of pediatric patients. PATIENT CONCERNS: We observed a pair of fraternal twins, in which the younger sister had AD, while the elder one had no relevant medical history. At present, the height of the 2 individuals is significantly inconsistent, with a difference of about 10 cm. DIAGNOSES: Based on the little patient’s medical history and clinical manifestations, the diagnosis of AD was made. INTERVENTIONS: This little patient was treated with oral routine antihistamines, topical glucocorticoids and Dupilumab. OUTCOMES: At present, her rash and xerosis have significant improvement. She also have relief of generalized itching and improved sleep quality. LESSONS: Previous studies have indeed shown that AD has a negative impact on children’s height. This case leads us to consider the association between AD and height. It also gave us the opportunity to observe subsequent height changes after the intervention was carried out.