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Shortcut barcoding and early pooling for scalable multiplex single-cell reduced-representation CpG methylation sequencing at single nucleotide resolution

DNA methylation is essential for a wide variety of biological processes, yet the development of a highly efficient and robust technology remains a challenge for routine single-cell analysis. We developed a multiplex scalable single-cell reduced representation bisulfite sequencing (msRRBS) technology...

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Detalles Bibliográficos
Autores principales: Mai, Liyao, Wen, Zebin, Zhang, Yulong, Gao, Yu, Lin, Guanchuan, Lian, Zhiwei, Yang, Xiang, Zhou, Jingjing, Lin, Xianwei, Luo, Chaochao, Peng, Wanwan, Chen, Caiming, Peng, Jiajia, Liu, Duolian, Marjani, Sadie L, Tao, Qian, Cui, Yongping, Zhang, Junxiao, Wu, Xuedong, Weissman, Sherman M, Pan, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681715/
https://www.ncbi.nlm.nih.gov/pubmed/37870443
http://dx.doi.org/10.1093/nar/gkad892