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The SAP domain of Ku facilitates its efficient loading onto DNA ends

The evolutionarily conserved DNA repair complex Ku serves as the primary sensor of free DNA ends in eukaryotic cells. Its rapid association with DNA ends is crucial for several cellular processes, including non-homologous end joining (NHEJ) DNA repair and telomere protection. In this study, we condu...

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Detalles Bibliográficos
Autores principales:	Fulneček, Jaroslav, Klimentová, Eva, Cairo, Albert, Bukovcakova, Sona Valuchova, Alexiou, Panagiotis, Prokop, Zbynek, Riha, Karel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681742/ https://www.ncbi.nlm.nih.gov/pubmed/37850645 http://dx.doi.org/10.1093/nar/gkad850

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