To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis

Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyro...

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Detalles Bibliográficos
Autores principales: Ahuja, Tania, Nuti, Olivia, Kemal, Cameron, Kang, Darren, Yuriditsky, Eugene, Horowitz, James M., Pashun, Raymond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681774/
https://www.ncbi.nlm.nih.gov/pubmed/38026474
http://dx.doi.org/10.1155/2023/1563732
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author Ahuja, Tania
Nuti, Olivia
Kemal, Cameron
Kang, Darren
Yuriditsky, Eugene
Horowitz, James M.
Pashun, Raymond A.
author_facet Ahuja, Tania
Nuti, Olivia
Kemal, Cameron
Kang, Darren
Yuriditsky, Eugene
Horowitz, James M.
Pashun, Raymond A.
author_sort Ahuja, Tania
collection PubMed
description Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy.
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spelling pubmed-106817742023-11-20 To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis Ahuja, Tania Nuti, Olivia Kemal, Cameron Kang, Darren Yuriditsky, Eugene Horowitz, James M. Pashun, Raymond A. Case Rep Cardiol Case Report Amiodarone-induced thyrotoxicosis (AIT) carries significant cardiovascular morbidity. There are two types of AIT with treatment including antithyroid medications and corticosteroids and treatment of ventricular arrhythmias. Therapeutic plasma exchange (TPE) also known as “PLEX” may help remove thyroid hormones and amiodarone. We report a case of PLEX in an attempt to treat cardiogenic shock secondary to AIT. This case highlights the robust rapidly deleterious demise of AIT, specifically in patients with decompensated heart failure. The decision to PLEX or not to PLEX for AIT should be individualized, prior to definitive therapy. Hindawi 2023-11-20 /pmc/articles/PMC10681774/ /pubmed/38026474 http://dx.doi.org/10.1155/2023/1563732 Text en Copyright © 2023 Tania Ahuja et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ahuja, Tania
Nuti, Olivia
Kemal, Cameron
Kang, Darren
Yuriditsky, Eugene
Horowitz, James M.
Pashun, Raymond A.
To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_full To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_fullStr To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_full_unstemmed To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_short To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
title_sort to plex or not to plex for amiodarone-induced thyrotoxicosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681774/
https://www.ncbi.nlm.nih.gov/pubmed/38026474
http://dx.doi.org/10.1155/2023/1563732
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