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Myelin insults differentials on MRI in children: In the light of an ADEM case

Acute disseminated encephalomyelitis (ADEM) is an acute and rapidly progressive auto-immune demyelinating disorder in the central nervous system. It is a rare disease but is more frequently observed in the pediatric population. We report a case of a monophasic postvaccination ADEM, which presented w...

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Detalles Bibliográficos
Autores principales: Naggar, Amine, Laasri, Khadija, Kabila, Badr, Izi, Zineb, Allali, Nazik, Haddad, Siham El, Chat, Latifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681876/
https://www.ncbi.nlm.nih.gov/pubmed/38033671
http://dx.doi.org/10.1016/j.radcr.2023.08.107
Descripción
Sumario:Acute disseminated encephalomyelitis (ADEM) is an acute and rapidly progressive auto-immune demyelinating disorder in the central nervous system. It is a rare disease but is more frequently observed in the pediatric population. We report a case of a monophasic postvaccination ADEM, which presented with paraparesis associated with fever. It showed a favorable evolution under corticosteroids, without recurrence after 3 years of follow-up. The diagnosis was established due to the postvaccination context and the MRI abnormalities characteristics. This case prompted a general discussion about the etiologies of myelin insults in children, especially demyelinating disorders, by shedding the light on their MRI features.