An “off-the-shelf” CD2 universal CAR-T therapy for T-cell malignancies

T-cell malignancies are associated with frequent relapse and high morbidity, which is partly due to the lack of effective or targeted treatment options. To broaden the use of CAR-T cells in pan T-cell malignancies, we developed an allogeneic “universal” CD2-targeting CAR-T cell (UCART2), in which th...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiang, Jingyu, Devenport, Jessica M., Carter, Alun J., Staser, Karl W., Kim, Miriam Y., O’ Neal, Julie, Ritchey, Julie K., Rettig, Michael P., Gao, Feng, Rettig, Garrett, Turk, Rolf, Lee, Byung Ha, Cooper, Matthew L., DiPersio, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681896/
https://www.ncbi.nlm.nih.gov/pubmed/37798328
http://dx.doi.org/10.1038/s41375-023-02039-z

Ejemplares similares

Ejemplares similares