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RNA helicase EIF4A1-mediated translation is essential for the GC response

EIF4A1 and cofactors EIF4B and EIF4H have been well characterised in cancers, including B cell malignancies, for their ability to promote the translation of oncogenes with structured 5′ untranslated regions. However, very little is known of their roles in nonmalignant cells. Using mouse models to de...

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Detalles Bibliográficos
Autores principales: Screen, Michael, Matheson, Louise S, Howden, Andrew JM, Strathdee, Douglas, Willis, Anne E, Bushell, Martin, Sansom, Owen, Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681908/
https://www.ncbi.nlm.nih.gov/pubmed/38011999
http://dx.doi.org/10.26508/lsa.202302301