Treatment of calcific arterial disease via enhancement of autophagy using GSK343

Vascular calcification is a hallmark of atherosclerotic disease and serves as a strong predictor and risk factor for cardiovascular events. Growing evidence suggests that autophagy may play a protective role in early atherosclerosis. The precise effects of autophagy on VSMC-mediated calcification re...

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Detalles Bibliográficos
Autores principales: Lino Cardenas, Christian L., Jiang, Wanlin, Kajuluri, Lova P., Singh, Kuldeep, Ostrom, Katrina, Li, Rebecca, Cherbonneau, Francois, Boerboom, Sophie, Birchenough, Claire, Roh, Kangsan, Chou, Elizabeth L., Shahrooz, Zarbafian, Nicholson, Christopher, Johnson, Adam L., Lee, Sujin, Ichinose, Fumito, Bloch, Donald B., Nigwekar, Sagar, Ellinor, Patrick T., Musolino, Patricia, Lindsay, Mark E., Dou, Zhixun, Miller, Clint L., Malhotra, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681952/
https://www.ncbi.nlm.nih.gov/pubmed/38033629
http://dx.doi.org/10.1016/j.isci.2023.108360

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