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Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation

Dysregulation of the ubiquitin-proteasome system has been implicated in the pathogenesis of several metabolic disorders, including obesity, diabetes, and non-alcoholic fatty liver disease; however, the mechanisms controlling pathogenic metabolic disorders remain unclear. Transcription factor CCAAT/e...

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Detalles Bibliográficos
Autores principales: Kim, Myung Sup, Baek, Jung-Hwan, Lee, JinAh, Sivaraman, Aneesh, Lee, Kyeong, Chun, Kyung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681981/
https://www.ncbi.nlm.nih.gov/pubmed/38012162
http://dx.doi.org/10.1038/s41419-023-06317-7

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