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Development of an early alert model for pandemic situations in Germany

The COVID-19 pandemic has pointed out the need for new technical approaches to increase the preparedness of healthcare systems. One important measure is to develop innovative early warning systems. Along those lines, we first compiled a corpus of relevant COVID-19 related symptoms with the help of a...

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Autores principales: Wang, Danqi, Lentzen, Manuel, Botz, Jonas, Valderrama, Diego, Deplante, Lucille, Perrio, Jules, Génin, Marie, Thommes, Edward, Coudeville, Laurent, Fröhlich, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682010/
https://www.ncbi.nlm.nih.gov/pubmed/38012282
http://dx.doi.org/10.1038/s41598-023-48096-3
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author Wang, Danqi
Lentzen, Manuel
Botz, Jonas
Valderrama, Diego
Deplante, Lucille
Perrio, Jules
Génin, Marie
Thommes, Edward
Coudeville, Laurent
Fröhlich, Holger
author_facet Wang, Danqi
Lentzen, Manuel
Botz, Jonas
Valderrama, Diego
Deplante, Lucille
Perrio, Jules
Génin, Marie
Thommes, Edward
Coudeville, Laurent
Fröhlich, Holger
author_sort Wang, Danqi
collection PubMed
description The COVID-19 pandemic has pointed out the need for new technical approaches to increase the preparedness of healthcare systems. One important measure is to develop innovative early warning systems. Along those lines, we first compiled a corpus of relevant COVID-19 related symptoms with the help of a disease ontology, text mining and statistical analysis. Subsequently, we applied statistical and machine learning (ML) techniques to time series data of symptom related Google searches and tweets spanning the time period from March 2020 to June 2022. In conclusion, we found that a long-short-term memory (LSTM) jointly trained on COVID-19 symptoms related Google Trends and Twitter data was able to accurately forecast up-trends in classical surveillance data (confirmed cases and hospitalization rates) 14 days ahead. In both cases, F1 scores were above 98% and 97%, respectively, hence demonstrating the potential of using digital traces for building an early alert system for pandemics in Germany.
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spelling pubmed-106820102023-11-30 Development of an early alert model for pandemic situations in Germany Wang, Danqi Lentzen, Manuel Botz, Jonas Valderrama, Diego Deplante, Lucille Perrio, Jules Génin, Marie Thommes, Edward Coudeville, Laurent Fröhlich, Holger Sci Rep Article The COVID-19 pandemic has pointed out the need for new technical approaches to increase the preparedness of healthcare systems. One important measure is to develop innovative early warning systems. Along those lines, we first compiled a corpus of relevant COVID-19 related symptoms with the help of a disease ontology, text mining and statistical analysis. Subsequently, we applied statistical and machine learning (ML) techniques to time series data of symptom related Google searches and tweets spanning the time period from March 2020 to June 2022. In conclusion, we found that a long-short-term memory (LSTM) jointly trained on COVID-19 symptoms related Google Trends and Twitter data was able to accurately forecast up-trends in classical surveillance data (confirmed cases and hospitalization rates) 14 days ahead. In both cases, F1 scores were above 98% and 97%, respectively, hence demonstrating the potential of using digital traces for building an early alert system for pandemics in Germany. Nature Publishing Group UK 2023-11-27 /pmc/articles/PMC10682010/ /pubmed/38012282 http://dx.doi.org/10.1038/s41598-023-48096-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Wang, Danqi
Lentzen, Manuel
Botz, Jonas
Valderrama, Diego
Deplante, Lucille
Perrio, Jules
Génin, Marie
Thommes, Edward
Coudeville, Laurent
Fröhlich, Holger
Development of an early alert model for pandemic situations in Germany
title Development of an early alert model for pandemic situations in Germany
title_full Development of an early alert model for pandemic situations in Germany
title_fullStr Development of an early alert model for pandemic situations in Germany
title_full_unstemmed Development of an early alert model for pandemic situations in Germany
title_short Development of an early alert model for pandemic situations in Germany
title_sort development of an early alert model for pandemic situations in germany
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682010/
https://www.ncbi.nlm.nih.gov/pubmed/38012282
http://dx.doi.org/10.1038/s41598-023-48096-3
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