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Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2

Hydroxycarboxylic acid receptor 2 (HCAR2) belongs to the family of class A G protein-coupled receptors with key roles in regulating lipolysis and free fatty acid formation in humans. It is deeply involved in many pathophysiological processes and serves as an attractive target for the treatment of ca...

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Detalles Bibliográficos
Autores principales: Pan, Xin, Ye, Fang, Ning, Peiruo, Zhang, Zhiyi, Li, Xinyu, Zhang, Binghao, Wang, Qian, Chen, Geng, Gao, Wei, Qiu, Chen, Wu, Zhangsong, Li, Jiancheng, Zhu, Lizhe, Xia, Jiang, Gong, Kaizheng, Du, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682194/
https://www.ncbi.nlm.nih.gov/pubmed/38012147
http://dx.doi.org/10.1038/s41421-023-00610-7