Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells

BACKGROUND: Prenatal exposure to elevated interleukin (IL)-6 levels is associated with increased risk for psychiatric disorders with a putative neurodevelopmental origin, such as schizophrenia (SZ), autism spectrum condition (ASC) and bipolar disorder (BD). Although rodent models provide causal evid...

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Detalles Bibliográficos
Autores principales: Couch, Amalie C.M., Solomon, Shiden, Duarte, Rodrigo R.R., Marrocu, Alessia, Sun, Yiqing, Sichlinger, Laura, Matuleviciute, Rugile, Polit, Lucia Dutan, Hanger, Bjørn, Brown, Amelia, Kordasti, Shahram, Srivastava, Deepak P., Vernon, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682389/
https://www.ncbi.nlm.nih.gov/pubmed/36781081
http://dx.doi.org/10.1016/j.bbi.2023.02.007

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