Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking

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The underlying genetic and epigenetic mechanisms driving functional adaptations in neuronal excitability and excessive alcohol intake are poorly understood. Small-conductance Ca(2+)-activated K(+) (K(Ca)2 or SK) channels encoded by the KCNN family of genes have emerged from preclinical studies as a...

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Detalles Bibliográficos
Autores principales: Mulholland, Patrick J., Padula, Audrey E., Wilhelm, Larry J., Park, Byung, Grant, Kathleen A., Ferguson, Betsy M., Cervera-Juanes, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682415/
https://www.ncbi.nlm.nih.gov/pubmed/38012158
http://dx.doi.org/10.1038/s41398-023-02676-z
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