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Lectin‐anticancer peptide fusion demonstrates a significant cancer‐cell‐selective cytotoxic effect and inspires the production of “clickable” anticancer peptide in Escherichia coli

Targeted killing of tumor cells while protecting healthy cells is the pressing priority in cancer treatment. Lectins that target a specific glycan marker abundant in cancer cells can be valuable new tools for selective cancer cell killing. The lectin Shiga‐like toxin 1 B subunit (Stx1B) is an exampl...

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Detalles Bibliográficos
Autores principales: Pasupuleti, Rajeev, Riedl, Sabrina, Saltor Núñez, Laia, Karava, Marianna, Kumar, Vajinder, Kourist, Robert, Turnbull, W. Bruce, Zweytick, Dagmar, Wiltschi, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MJohn Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682692/
https://www.ncbi.nlm.nih.gov/pubmed/37916438
http://dx.doi.org/10.1002/pro.4830