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The role and mechanism of TCM in the prevention and treatment of infectious diseases

The constant presence of infectious diseases poses an everlasting threat to the entire world. In recent years, there has been an increased attention toward the application of traditional Chinese medicine (TCM) in the treatment of emerging infectious diseases, as it has played a significant role. The...

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Autores principales: Zou, Qifei, Chen, Yitong, Qin, Huanxin, Tang, Rui, Han, Taojian, Guo, Ziyi, Zhao, Juanjuan, Xu, Delin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682724/
https://www.ncbi.nlm.nih.gov/pubmed/38033575
http://dx.doi.org/10.3389/fmicb.2023.1286364
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author Zou, Qifei
Chen, Yitong
Qin, Huanxin
Tang, Rui
Han, Taojian
Guo, Ziyi
Zhao, Juanjuan
Xu, Delin
author_facet Zou, Qifei
Chen, Yitong
Qin, Huanxin
Tang, Rui
Han, Taojian
Guo, Ziyi
Zhao, Juanjuan
Xu, Delin
author_sort Zou, Qifei
collection PubMed
description The constant presence of infectious diseases poses an everlasting threat to the entire world. In recent years, there has been an increased attention toward the application of traditional Chinese medicine (TCM) in the treatment of emerging infectious diseases, as it has played a significant role. The aim of this article is to provide a concise overview of the roles and mechanisms of TCM in treating infectious diseases. TCM possesses the ability to modulate relevant factors, impede signaling pathways, and inhibit microbial growth, thereby exhibiting potent antiviral, antibacterial, and anti-inflammatory effects that demonstrate remarkable efficacy against viral and bacterial infections. This article concludes that the comprehensive regulatory features of Chinese herbal medicines, with their various components, targets, and pathways, result in synergistic effects. The significance of Chinese herbal medicines in the context of infectious diseases should not be underestimated; however, it is crucial to also acknowledge their underutilization. This paper presents constructive suggestions regarding the challenges and opportunities faced by Chinese medicines. Particularly, it emphasizes the effectiveness and characteristics of Chinese medicines in the treatment of infectious diseases, specifying how these medicines’ active substances can be utilized to target infectious diseases. This perspective is advantageous in facilitating researchers’ pharmacological studies on Chinese medicines, focusing on the specific points of action. The mechanism of action of Chinese herbal medicines in the treatment of infectious diseases is comprehensively elucidated in this paper, providing compelling evidence for the superior treatment of infectious diseases through Chinese medicine. This information is favorable for advancing the development of TCM and its potential applications in the field of infectious diseases.
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spelling pubmed-106827242023-11-30 The role and mechanism of TCM in the prevention and treatment of infectious diseases Zou, Qifei Chen, Yitong Qin, Huanxin Tang, Rui Han, Taojian Guo, Ziyi Zhao, Juanjuan Xu, Delin Front Microbiol Microbiology The constant presence of infectious diseases poses an everlasting threat to the entire world. In recent years, there has been an increased attention toward the application of traditional Chinese medicine (TCM) in the treatment of emerging infectious diseases, as it has played a significant role. The aim of this article is to provide a concise overview of the roles and mechanisms of TCM in treating infectious diseases. TCM possesses the ability to modulate relevant factors, impede signaling pathways, and inhibit microbial growth, thereby exhibiting potent antiviral, antibacterial, and anti-inflammatory effects that demonstrate remarkable efficacy against viral and bacterial infections. This article concludes that the comprehensive regulatory features of Chinese herbal medicines, with their various components, targets, and pathways, result in synergistic effects. The significance of Chinese herbal medicines in the context of infectious diseases should not be underestimated; however, it is crucial to also acknowledge their underutilization. This paper presents constructive suggestions regarding the challenges and opportunities faced by Chinese medicines. Particularly, it emphasizes the effectiveness and characteristics of Chinese medicines in the treatment of infectious diseases, specifying how these medicines’ active substances can be utilized to target infectious diseases. This perspective is advantageous in facilitating researchers’ pharmacological studies on Chinese medicines, focusing on the specific points of action. The mechanism of action of Chinese herbal medicines in the treatment of infectious diseases is comprehensively elucidated in this paper, providing compelling evidence for the superior treatment of infectious diseases through Chinese medicine. This information is favorable for advancing the development of TCM and its potential applications in the field of infectious diseases. Frontiers Media S.A. 2023-11-14 /pmc/articles/PMC10682724/ /pubmed/38033575 http://dx.doi.org/10.3389/fmicb.2023.1286364 Text en Copyright © 2023 Zou, Chen, Qin, Tang, Han, Guo, Zhao and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Zou, Qifei
Chen, Yitong
Qin, Huanxin
Tang, Rui
Han, Taojian
Guo, Ziyi
Zhao, Juanjuan
Xu, Delin
The role and mechanism of TCM in the prevention and treatment of infectious diseases
title The role and mechanism of TCM in the prevention and treatment of infectious diseases
title_full The role and mechanism of TCM in the prevention and treatment of infectious diseases
title_fullStr The role and mechanism of TCM in the prevention and treatment of infectious diseases
title_full_unstemmed The role and mechanism of TCM in the prevention and treatment of infectious diseases
title_short The role and mechanism of TCM in the prevention and treatment of infectious diseases
title_sort role and mechanism of tcm in the prevention and treatment of infectious diseases
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682724/
https://www.ncbi.nlm.nih.gov/pubmed/38033575
http://dx.doi.org/10.3389/fmicb.2023.1286364
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