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A mode of action-based probabilistic framework of dose-response assessment for nonmutagenic liver carcinogens: a case study of PCB-126
A main function of dose-response assessment is to estimate a “safe” dose in the target population to support chemical risk assessment. Typically, a “safe” dose is developed differently for cancer and noncancer effects based on a 2-step procedure, ie, point of departure (POD) derivation and low-dose...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682966/ https://www.ncbi.nlm.nih.gov/pubmed/37643630 http://dx.doi.org/10.1093/toxsci/kfad091 |