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Amino Acids as Chelating Ligands for Platinum: Enhanced Stability in an Aqueous Environment Promoted by Biocompatible Molecules

[Image: see text] Platinum-based chemotherapeutics are a cornerstone in the treatment of many malignancies. However, their dose-limiting side effects have rooted efforts to develop new drug candidates with higher selectivity for tumor tissues and less problematic side effects. Here, we developed a c...

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Detalles Bibliográficos
Autores principales: Cucchiaro, Andrea, Scherfler, Amelie, Corinti, Davide, Berden, Giel, Oomens, Jos, Wurst, Klaus, Gust, Ronald, Crestoni, Maria Elisa, Kircher, Brigitte, Cziferszky, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683014/
https://www.ncbi.nlm.nih.gov/pubmed/37937969
http://dx.doi.org/10.1021/acs.jmedchem.3c01340

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