METTL3-mediated m6A RNA methylation induces the differentiation of lung resident mesenchymal stem cells into myofibroblasts via the miR-21/PTEN pathway

BACKGROUND: The accumulation of myofibroblasts is the key pathological feature of pulmonary fibrosis (PF). Aberrant differentiation of lung-resident mesenchymal stem cells (LR-MSCs) has been identified as a critical source of myofibroblasts, but the molecular mechanisms underlying this process remai...

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Detalles Bibliográficos
Autores principales: Lu, Yi, Liu, Zeyu, Zhang, Yunjiao, Wu, Xiuhua, Bian, Wei, Shan, Shan, Yang, Danrong, Ren, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683095/
https://www.ncbi.nlm.nih.gov/pubmed/38017523
http://dx.doi.org/10.1186/s12931-023-02606-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683095/
https://www.ncbi.nlm.nih.gov/pubmed/38017523
http://dx.doi.org/10.1186/s12931-023-02606-z

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