Ginseng-derived nanoparticles reprogram macrophages to regulate arginase-1 release for ameliorating T cell exhaustion in tumor microenvironment

BACKGROUND: Lines of evidence indicated that, immune checkpoints (ICs) inhibitors enhanced T cell immune response to exert anti-tumor effects. However, T cell exhaustion has been so far a major obstacle to antitumor immunotherapy in colorectal cancer patients. Our previous studies showed that ginsen...

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Detalles Bibliográficos
Autores principales: Lv, Yan, Li, Mengyuan, Weng, Ling, Huang, Haoying, Mao, Yujie, Yang, Danchen Aaron, Wei, Qingyun, Zhao, Mengmeng, Wei, Qin, Rui, Ke, Han, Xuan, Fan, Weiwei, Cai, Xueting, Cao, Peng, Cao, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683135/
https://www.ncbi.nlm.nih.gov/pubmed/38012650
http://dx.doi.org/10.1186/s13046-023-02888-7

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