Detection of continuous hierarchical heterogeneity by single-cell surface antigen analysis in the prognosis evaluation of acute myeloid leukaemia

BACKGROUND: Acute myeloid leukaemia (AML) is characterised by the malignant accumulation of myeloid progenitors with a high recurrence rate after chemotherapy. Blasts (leukaemia cells) exhibit a complete myeloid differentiation hierarchy hiding a wide range of temporal information from initial to ma...

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Detalles Bibliográficos
Autores principales: Shao, Nan, Ren, Chenshuo, Hu, Tianyuan, Wang, Dianbing, Zhu, Xiaofan, Li, Min, Cheng, Tao, Zhang, Yingchi, Zhang, Xian-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683216/
https://www.ncbi.nlm.nih.gov/pubmed/38017410
http://dx.doi.org/10.1186/s12859-023-05561-0

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