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Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
The advent of iPSCs has brought about a significant transformation in stem cell research, opening up promising avenues for advancing cancer treatment. The formation of cancer is a multifaceted process influenced by genetic, epigenetic, and environmental factors. iPSCs offer a distinctive platform fo...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683363/ https://www.ncbi.nlm.nih.gov/pubmed/38017433 http://dx.doi.org/10.1186/s12943-023-01873-0 |
| _version_ | 1785151179911593984 |
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| author | Chehelgerdi, Matin Behdarvand Dehkordi, Fereshteh Chehelgerdi, Mohammad Kabiri, Hamidreza Salehian-Dehkordi, Hosein Abdolvand, Mohammad Salmanizadeh, Sharareh Rashidi, Mohsen Niazmand, Anoosha Ahmadi, Saba Feizbakhshan, Sara Kabiri, Saber Vatandoost, Nasimeh Ranjbarnejad, Tayebeh |
| author_facet | Chehelgerdi, Matin Behdarvand Dehkordi, Fereshteh Chehelgerdi, Mohammad Kabiri, Hamidreza Salehian-Dehkordi, Hosein Abdolvand, Mohammad Salmanizadeh, Sharareh Rashidi, Mohsen Niazmand, Anoosha Ahmadi, Saba Feizbakhshan, Sara Kabiri, Saber Vatandoost, Nasimeh Ranjbarnejad, Tayebeh |
| author_sort | Chehelgerdi, Matin |
| collection | PubMed |
| description | The advent of iPSCs has brought about a significant transformation in stem cell research, opening up promising avenues for advancing cancer treatment. The formation of cancer is a multifaceted process influenced by genetic, epigenetic, and environmental factors. iPSCs offer a distinctive platform for investigating the origin of cancer, paving the way for novel approaches to cancer treatment, drug testing, and tailored medical interventions. This review article will provide an overview of the science behind iPSCs, the current limitations and challenges in iPSC-based cancer therapy, the ethical and social implications, and the comparative analysis with other stem cell types for cancer treatment. The article will also discuss the applications of iPSCs in tumorigenesis, the future of iPSCs in tumorigenesis research, and highlight successful case studies utilizing iPSCs in tumorigenesis research. The conclusion will summarize the advancements made in iPSC-based tumorigenesis research and the importance of continued investment in iPSC research to unlock the full potential of these cells. |
| format | Online Article Text |
| id | pubmed-10683363 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-106833632023-11-30 Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy Chehelgerdi, Matin Behdarvand Dehkordi, Fereshteh Chehelgerdi, Mohammad Kabiri, Hamidreza Salehian-Dehkordi, Hosein Abdolvand, Mohammad Salmanizadeh, Sharareh Rashidi, Mohsen Niazmand, Anoosha Ahmadi, Saba Feizbakhshan, Sara Kabiri, Saber Vatandoost, Nasimeh Ranjbarnejad, Tayebeh Mol Cancer Review The advent of iPSCs has brought about a significant transformation in stem cell research, opening up promising avenues for advancing cancer treatment. The formation of cancer is a multifaceted process influenced by genetic, epigenetic, and environmental factors. iPSCs offer a distinctive platform for investigating the origin of cancer, paving the way for novel approaches to cancer treatment, drug testing, and tailored medical interventions. This review article will provide an overview of the science behind iPSCs, the current limitations and challenges in iPSC-based cancer therapy, the ethical and social implications, and the comparative analysis with other stem cell types for cancer treatment. The article will also discuss the applications of iPSCs in tumorigenesis, the future of iPSCs in tumorigenesis research, and highlight successful case studies utilizing iPSCs in tumorigenesis research. The conclusion will summarize the advancements made in iPSC-based tumorigenesis research and the importance of continued investment in iPSC research to unlock the full potential of these cells. BioMed Central 2023-11-28 /pmc/articles/PMC10683363/ /pubmed/38017433 http://dx.doi.org/10.1186/s12943-023-01873-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
| spellingShingle | Review Chehelgerdi, Matin Behdarvand Dehkordi, Fereshteh Chehelgerdi, Mohammad Kabiri, Hamidreza Salehian-Dehkordi, Hosein Abdolvand, Mohammad Salmanizadeh, Sharareh Rashidi, Mohsen Niazmand, Anoosha Ahmadi, Saba Feizbakhshan, Sara Kabiri, Saber Vatandoost, Nasimeh Ranjbarnejad, Tayebeh Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy |
| title | Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy |
| title_full | Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy |
| title_fullStr | Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy |
| title_full_unstemmed | Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy |
| title_short | Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy |
| title_sort | exploring the promising potential of induced pluripotent stem cells in cancer research and therapy |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683363/ https://www.ncbi.nlm.nih.gov/pubmed/38017433 http://dx.doi.org/10.1186/s12943-023-01873-0 |
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