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Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo
INTRODUCTION: liver Transplantation is currently the treatment of choice for several terminal liver diseases. Despite the increase in performed transplants, the waiting lists continue to increase. In order to expand the supply of organs, transplantation teams have started to use previously rejected...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Colégio Brasileiro de Cirurgiões
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683471/ https://www.ncbi.nlm.nih.gov/pubmed/33978120 http://dx.doi.org/10.1590/0100-6991e-20202492 |
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author | LUGON FERREIRA-JR, ANTONIO CARLOS MIGUEL, GUSTAVO PEIXOTO SOARES MOSCON, IARA ABREU, ISAAC WALKER AGUIAR, JULIETE BOREL DE OLIVEIRA SILVA VECCI, THALES RIBEIRO DOS SANTOS |
author_facet | LUGON FERREIRA-JR, ANTONIO CARLOS MIGUEL, GUSTAVO PEIXOTO SOARES MOSCON, IARA ABREU, ISAAC WALKER AGUIAR, JULIETE BOREL DE OLIVEIRA SILVA VECCI, THALES RIBEIRO DOS SANTOS |
author_sort | LUGON FERREIRA-JR, ANTONIO CARLOS |
collection | PubMed |
description | INTRODUCTION: liver Transplantation is currently the treatment of choice for several terminal liver diseases. Despite the increase in performed transplants, the waiting lists continue to increase. In order to expand the supply of organs, transplantation teams have started to use previously rejected livers for transplants because of an increased risk of unfavorable outcomes. OBJECTIVE: to evaluate the use of livers of expanded criterion donators. METHODS: retrospective study of medical records. The livers were classified as normal or expanded criteria. The groups were divided in low and high MELD. A multivariate analysis was performed through logistic regression. RESULTS: there was no statistical difference regarding early, late and global mortality between the groups. Decreased survival was observed in patients with high MELD (higher or equal to 20) when they received grafts from expanded criterion donators. The association between the occurrence of cardiorespiratory arrest and presence of elevated total bilirubin in donators was associated with higher mortality rates in expanded criterion livers. CONCLUSION: the overall results are similar, but expanded criteria liver donators was associated with higher mortality in patients with high MELD. |
format | Online Article Text |
id | pubmed-10683471 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Colégio Brasileiro de Cirurgiões |
record_format | MEDLINE/PubMed |
spelling | pubmed-106834712023-11-30 Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo LUGON FERREIRA-JR, ANTONIO CARLOS MIGUEL, GUSTAVO PEIXOTO SOARES MOSCON, IARA ABREU, ISAAC WALKER AGUIAR, JULIETE BOREL DE OLIVEIRA SILVA VECCI, THALES RIBEIRO DOS SANTOS Rev Col Bras Cir Original Article INTRODUCTION: liver Transplantation is currently the treatment of choice for several terminal liver diseases. Despite the increase in performed transplants, the waiting lists continue to increase. In order to expand the supply of organs, transplantation teams have started to use previously rejected livers for transplants because of an increased risk of unfavorable outcomes. OBJECTIVE: to evaluate the use of livers of expanded criterion donators. METHODS: retrospective study of medical records. The livers were classified as normal or expanded criteria. The groups were divided in low and high MELD. A multivariate analysis was performed through logistic regression. RESULTS: there was no statistical difference regarding early, late and global mortality between the groups. Decreased survival was observed in patients with high MELD (higher or equal to 20) when they received grafts from expanded criterion donators. The association between the occurrence of cardiorespiratory arrest and presence of elevated total bilirubin in donators was associated with higher mortality rates in expanded criterion livers. CONCLUSION: the overall results are similar, but expanded criteria liver donators was associated with higher mortality in patients with high MELD. Colégio Brasileiro de Cirurgiões 2021-04-24 /pmc/articles/PMC10683471/ /pubmed/33978120 http://dx.doi.org/10.1590/0100-6991e-20202492 Text en © 2021 Revista do Colégio Brasileiro de Cirurgiões https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Original Article LUGON FERREIRA-JR, ANTONIO CARLOS MIGUEL, GUSTAVO PEIXOTO SOARES MOSCON, IARA ABREU, ISAAC WALKER AGUIAR, JULIETE BOREL DE OLIVEIRA SILVA VECCI, THALES RIBEIRO DOS SANTOS Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo |
title | Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo |
title_full | Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo |
title_fullStr | Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo |
title_full_unstemmed | Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo |
title_short | Comparison of results on the use of extended criteria liver doners for transplants in Espírito Santo |
title_sort | comparison of results on the use of extended criteria liver doners for transplants in espírito santo |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683471/ https://www.ncbi.nlm.nih.gov/pubmed/33978120 http://dx.doi.org/10.1590/0100-6991e-20202492 |
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