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Offsetting Low-Affinity Carbohydrate Binding with Covalency to Engage Sugar-Specific Proteins for Tumor-Immune Proximity Induction

[Image: see text] Carbohydrate-binding receptors are often used by the innate immune system to potentiate inflammation, target endocytosis/destruction, and adaptive immunity (e.g., CD206, DC-SIGN, MBL, and anticarbohydrate antibodies). To access this class of receptors for cancer immunotherapy, a gr...

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Detalles Bibliográficos
Autores principales: Lake, Benjamin P. M., Rullo, Anthony F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683482/
https://www.ncbi.nlm.nih.gov/pubmed/38033792
http://dx.doi.org/10.1021/acscentsci.3c01052