Cargando…

Bispecific Antibody Detection Using Antigen-Conjugated Synthetic Nucleic Acid Strands

[Image: see text] We report here the development of two different sensing strategies based on the use of antigen-conjugated nucleic acid strands for the detection of a bispecific antibody against the tumor-related proteins Mucin1 and epidermal growth factor receptor. Both approaches work well in ser...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mariottini, Davide, Bracaglia, Sara, Barbero, Luca, Fuchs, Sebastian W., Saal, Christoph, Moniot, Sebastien, Knuehl, Christine, Baranda, Lorena, Ranallo, Simona, Ricci, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683503/ https://www.ncbi.nlm.nih.gov/pubmed/37856082 http://dx.doi.org/10.1021/acssensors.3c01717

Ejemplares similares

Synthetic Antigen-Conjugated DNA Systems for Antibody Detection and Characterization
por: Ranallo, Simona, et al.
Publicado: (2023)

Programmable, Multiplexed DNA Circuits Supporting Clinically Relevant, Electrochemical Antibody Detection
por: Bracaglia, Sara, et al.
Publicado: (2021)

Antibody-powered nucleic acid release using a DNA-based nanomachine
por: Ranallo, Simona, et al.
Publicado: (2017)

Thermo-Programmed Synthetic DNA-Based Receptors
por: Mariottini, Davide, et al.
Publicado: (2023)

Programmable Cell-Free Transcriptional Switches for Antibody Detection
por: Patino Diaz, Aitor, et al.
Publicado: (2022)

Novel Human Bispecific Aptamer–Antibody Conjugates for Efficient Cancer Cell Killing
por: Passariello, Margherita, et al.
Publicado: (2019)

Visualizing single-stranded nucleic acids in solution
por: Plumridge, Alex, et al.
Publicado: (2017)

Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
por: Ranallo, Simona, et al.
Publicado: (2019)

Publisher Correction: Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
por: Ranallo, Simona, et al.
Publicado: (2020)

Bispecific Antibodies and Antibody–Drug Conjugates for Cancer Therapy: Technological Considerations
por: Shim, Hyunbo
Publicado: (2020)

Computing in mammalian cells with nucleic acid strand exchange
por: Groves, Benjamin, et al.
Publicado: (2015)

Drug Conjugated and Bispecific Antibodies for Multiple Myeloma: Improving Immunotherapies off the Shelf
por: Barilà, Gregorio, et al.
Publicado: (2021)

Emerging Role of Antibody-Drug Conjugates and Bispecific Antibodies for the Treatment of Multiple Myeloma
por: Tai, Waqqas, et al.
Publicado: (2022)

Structural and Photophysical Templating of Conjugated Polyelectrolytes with Single-Stranded DNA
por: Peterhans, Lisa, et al.
Publicado: (2020)

Fully synthetic platform to rapidly generate tetravalent bispecific nanobody–based immunoglobulins
por: Misson Mindrebo, Laetitia, et al.
Publicado: (2023)

Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma
por: Märkl, Florian, et al.
Publicado: (2023)

A partition function algorithm for interacting nucleic acid strands
por: Chitsaz, Hamidreza, et al.
Publicado: (2009)

Availability: A Metric for Nucleic Acid Strand Displacement Systems
por: Olson, Xiaoping, et al.
Publicado: (2016)

Programming molecular topologies from single-stranded nucleic acids
por: Qi, Xiaodong, et al.
Publicado: (2018)

Optical and theoretical study of strand recognition by nucleic acid probes
por: Domljanovic, Ivana, et al.
Publicado: (2020)

Pressure Tuning Studies of Four-Stranded Nucleic Acid Structures
por: Smeller, László
Publicado: (2023)

Current and emerging monoclonal antibodies, antibody-drug conjugates, and bispecific antibodies in treatment of lymphoma
por: Atallah-Yunes, Suheil Albert, et al.
Publicado: (2022)

Design of nucleic acid strands with long low-barrier folding pathways
por: Condon, Anne, et al.
Publicado: (2017)

Recognition of single-stranded nucleic acids by small-molecule splicing modulators
por: Tang, Zhichao, et al.
Publicado: (2021)

Nucleic acid strand displacement – from DNA nanotechnology to translational regulation
por: Simmel, Friedrich C.
Publicado: (2023)

SYNTHETIC STRANDS OF CARDIAC MUSCLE : Formation and Ultrastructure
por: Purdy, Joyce E., et al.
Publicado: (1972)

Intracellular Fate of Spherical Nucleic Acid Nanoparticle Conjugates
por: Wu, Xiaochen A., et al.
Publicado: (2014)

Self-Assembly of Diphenylalanine–Peptide Nucleic Acid Conjugates
por: Datta, Dhrubajyoti, et al.
Publicado: (2019)

Electronic control of DNA-based nanoswitches and nanodevices
por: Ranallo, Simona, et al.
Publicado: (2016)

DNA double-strand break repair and nucleic acid-related immunity: DSB repair and nucleic acid-related immunity
por: Zhang, Haiping, et al.
Publicado: (2022)

Synthetic Life with Alternative Nucleic Acids as Genetic Materials
por: Nie, Peng, et al.
Publicado: (2020)

Modular Chemical Construction of IgG-like Mono- and Bispecific Synthetic Antibodies (SynAbs)
por: Thoreau, Fabien, et al.
Publicado: (2023)

A Suite of Therapeutically-Inspired Nucleic Acid Logic Systems for Conditional Generation of Single-Stranded and Double-Stranded Oligonucleotides
por: Zakrevsky, Paul, et al.
Publicado: (2019)

A bispecific monoclonal antibody against methotrexate and a human tumour associated antigen augments cytotoxicity of methotrexate-carrier conjugate.
por: Pimm, M. V., et al.
Publicado: (1990)

β-Strand inspired bifacial π-conjugated polymers
por: Chaudhuri, Saikat, et al.
Publicado: (2019)

Structure‐Guided Design of a Group B Streptococcus Type III Synthetic Glycan–Conjugate Vaccine
por: Oldrini, Davide, et al.
Publicado: (2020)

Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies
por: Samuelsen, Simone V., et al.
Publicado: (2016)

A Bispecific METxMET Antibody–Drug Conjugate with Cleavable Linker Is Processed in Recycling and Late Endosomes
por: Perez Bay, Andres E., et al.
Publicado: (2023)

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
por: Toh, Desiree-Faye Kaixin, et al.
Publicado: (2017)

Enhanced antigen immunogenicity induced by bispecific antibodies
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_i54pv91pcmmdvqgie2bnp6dven