Cargando…

Abnormal low expression of SFTPC promotes the proliferation of lung adenocarcinoma by enhancing PI3K/AKT/mTOR signaling transduction

The abnormality of surfactant protein C (SFTPC) has been linked to the development of a number of interstitial lung diseases, according to mounting evidence. Nonetheless, the function and mechanism of SFTPC in the biological progression of lung adenocarcinoma (LUAD) remain unclear. Analysis of publi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zuo, Baile, Wang, Lin, Li, Xiaoyan, Li, Xin, Wang, Jinping, Xiong, Yanlu, Lei, Jie, Zhang, Xi, Chen, Yifan, Liu, Qiongwen, Jiao, Jinke, Sui, Mengru, Fan, Jinhan, Wu, Ningxue, Song, Zewen, Li, Guoyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683597/ https://www.ncbi.nlm.nih.gov/pubmed/37955668 http://dx.doi.org/10.18632/aging.205191

Ejemplares similares

Tripartite motif 27 promotes cardiac hypertrophy via PTEN/Akt/mTOR signal pathways
por: Chen, Yan, et al.
Publicado: (2022)

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
por: Glaviano, Antonino, et al.
Publicado: (2023)

Oxidant Stress and Signal Transduction in the Nervous System with the PI 3-K, Akt, and mTOR Cascade
por: Maiese, Kenneth, et al.
Publicado: (2012)

Signal Transduction Pathways in Breast Cancer: The Important Role of PI3K/Akt/mTOR
por: Ortega, Miguel A., et al.
Publicado: (2020)

The Paradox of Akt-mTOR Interactions
por: Vadlakonda, Lakshmipathi, et al.
Publicado: (2013)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs: Effect of Akt/mTOR inhibition on PTEN expression
por: Wan, Linyan, et al.
Publicado: (2022)

Machine learning-based construction of immunogenic cell death-related score for improving prognosis and response to immunotherapy in melanoma
por: Li, Guoyin, et al.
Publicado: (2023)

Coordination of the AMPK, Akt, mTOR, and p53 Pathways under Glucose Starvation
por: Zhou, Yifan, et al.
Publicado: (2022)

Correlating SFTPC gene variants to interstitial lung disease in Egyptian children
por: Abdel Megeid, Azza K., et al.
Publicado: (2022)

Antihepatocarcinoma Effect of Portulaca oleracea L. in Mice by PI3K/Akt/mTOR and Nrf2/HO-1/NF-κB Pathway
por: Guoyin, Zheng, et al.
Publicado: (2017)

PODNL1 promotes cell proliferation and migration in glioma via regulating Akt/mTOR pathway
por: Geng, Yibo, et al.
Publicado: (2020)

Matrine induces autophagy in human neuroblastoma cells via blocking the AKT-mTOR pathway
por: Liu, Nanjing, et al.
Publicado: (2022)

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway
por: Li, Xiaoyan, et al.
Publicado: (2014)

Akt and mTOR in B Cell Activation and Differentiation
por: Limon, Jose J., et al.
Publicado: (2012)

Akt and mTOR mediate programmed necrosis in neurons
por: Liu, Q, et al.
Publicado: (2014)

Correction: Correlating SFTPC gene variants to interstitial lung disease in Egyptian children
por: Abdel Megeid, Azza K., et al.
Publicado: (2022)

Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy
por: Li, Xiaoyan, et al.
Publicado: (2023)

Zyxin promotes hepatocellular carcinoma progression via the activation of AKT/mTOR signaling pathway
por: CAI, TIANYING, et al.
Publicado: (2023)

Inhibition of apoptosis through AKT-mTOR pathway in ovarian cancer and renal cancer
por: Chen, Hongrun, et al.
Publicado: (2023)

Activation of Akt/mTOR Pathway Is Associated with Poor Prognosis of Nasopharyngeal Carcinoma
por: Wang, Weiyuan, et al.
Publicado: (2014)

Targeting the PI3K-AKT-mTOR signaling network in cancer
por: Khan, Khurum H., et al.
Publicado: (2013)

PI3K/AKT/mTOR Pathway in Angiogenesis
por: Karar, Jayashree, et al.
Publicado: (2011)

Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway
por: Zheng, Xiangjin, et al.
Publicado: (2021)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Regulates Neurite Outgrowth Through the Activation of Akt/mTOR and Erk/mTOR Signaling Pathways
por: Wen, Wen, et al.
Publicado: (2020)

Roles of Akt and ERK in mTOR-Dependent Antidepressant Effects of Vanillic Acid
por: Chuang, Han-Wen, et al.
Publicado: (2020)

Targeting AKT/mTOR in Oral Cancer: Mechanisms and Advances in Clinical Trials
por: Harsha, Choudhary, et al.
Publicado: (2020)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity
por: Yao, Chong, et al.
Publicado: (2018)

Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer
por: Li, Huayi, et al.
Publicado: (2021)

CDCA2 Promotes HCC Cells Development via AKT–mTOR Pathway
por: Li, Kai, et al.
Publicado: (2022)

Rab22a Promotes Epithelial-Mesenchymal Transition in Papillary Thyroid Carcinoma by Activating PI3K/AKT/mTOR Signaling Pathway
por: Luo, Xue, et al.
Publicado: (2022)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

Aldose reductase interacts with AKT1 to augment hepatic AKT/mTOR signaling and promote hepatocarcinogenesis
por: Zhao, Jia-Xing, et al.
Publicado: (2017)

Association of BAFF with PI3K/Akt/mTOR signaling in lupus nephritis
por: Ge, Fengmei, et al.
Publicado: (2017)

Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt/mTOR Signaling
por: Xu, Jing, et al.
Publicado: (2019)

Crystal Deposits in Macrophages and Distal Lung Remodeling: A Tale of Aging in SFTPC-Deficient Mice
por: Weng, Tingting, et al.
Publicado: (2020)

An SFTPC gene mutation causes childhood interstitial lung disease: first report in the Arab region
por: Alzaid, Mohammed A, et al.
Publicado: (2020)

Induced Pluripotent Stem Cell-derived Alveolar Type II Heterogeneity: Revealed by SFTPC Expression
por: Mou, Hongmei
Publicado: (2021)

Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway
por: Qiao, Hong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hbdj9lgccf5he2glbi02iqku0l