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Computational analysis of the functional and structural impact of the most deleterious missense mutations in the human Protein C
Protein C (PC) is a vitamin K-dependent factor that plays a crucial role in controlling anticoagulant processes and acts as a cytoprotective agent to promote cell survival. Several mutations in human PC are associated with decreased protein production or altered protein structure, resulting in PC de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683990/ https://www.ncbi.nlm.nih.gov/pubmed/38015884 http://dx.doi.org/10.1371/journal.pone.0294417 |