Cargando…
Computational analysis of the functional and structural impact of the most deleterious missense mutations in the human Protein C
Protein C (PC) is a vitamin K-dependent factor that plays a crucial role in controlling anticoagulant processes and acts as a cytoprotective agent to promote cell survival. Several mutations in human PC are associated with decreased protein production or altered protein structure, resulting in PC de...
Autores principales: | Farajzadeh-Dehkordi, Mahvash, Mafakher, Ladan, Harifi, Abbas, Samiee-Rad, Fatemeh, Rahmani, Babak |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683990/ https://www.ncbi.nlm.nih.gov/pubmed/38015884 http://dx.doi.org/10.1371/journal.pone.0294417 |
Ejemplares similares
-
Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact
por: Farajzadeh-Dehkordi, Mahvash, et al.
Publicado: (2023) -
Computational Identification of Most Deleterious Missense Mutations in Human PD-1 Gene
por: Ahmed Al-Madhagi, Haitham
Publicado: (2023) -
Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences
por: Emadi, Elaheh, et al.
Publicado: (2020) -
Computational SNP Analysis and Molecular Simulation Revealed the Most Deleterious Missense Variants in the NBD1 Domain of Human ABCA1 Transporter
por: Dash, Raju, et al.
Publicado: (2020) -
LIST-S2: taxonomy based sorting of deleterious missense mutations across species
por: Malhis, Nawar, et al.
Publicado: (2020)