Dexrazoxane does not mitigate early vascular toxicity induced by doxorubicin in mice

Apart from cardiotoxicity, the chemotherapeutic agent doxorubicin (DOX) provokes acute and long-term vascular toxicity. Dexrazoxane (DEXRA) is an effective drug for treatment of DOX-induced cardiotoxicity, yet it remains currently unknown whether DEXRA prevents vascular toxicity associated with DOX....

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Detalles Bibliográficos
Autores principales: Bosman, Matthias, Krüger, Dustin N., Favere, Kasper, De Meyer, Guido R. Y., Franssen, Constantijn, Van Craenenbroeck, Emeline M., Guns, Pieter-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684076/
https://www.ncbi.nlm.nih.gov/pubmed/38015959
http://dx.doi.org/10.1371/journal.pone.0294848

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