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Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study

Systemic inflammatory responses and nutritional status are useful prognostic factors in gastric cancer patients. Since oral hypofunction causes undernutrition, we cross-sectionally investigated whether nutritional biomarkers were affected by the occlusal supporting zone status. In 114 gastric cancer...

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Autores principales: Abe, Atsushi, Ito, Yu, Hayashi, Hiroki, Nakayama, Atsushi, Furuta, Hiroshi, Momokita, Moeko, Hasegawa, Hiroaki, Tsunoda, Akari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684134/
https://www.ncbi.nlm.nih.gov/pubmed/35356942
http://dx.doi.org/10.1097/MD.0000000000029094
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author Abe, Atsushi
Ito, Yu
Hayashi, Hiroki
Nakayama, Atsushi
Furuta, Hiroshi
Momokita, Moeko
Hasegawa, Hiroaki
Tsunoda, Akari
author_facet Abe, Atsushi
Ito, Yu
Hayashi, Hiroki
Nakayama, Atsushi
Furuta, Hiroshi
Momokita, Moeko
Hasegawa, Hiroaki
Tsunoda, Akari
author_sort Abe, Atsushi
collection PubMed
description Systemic inflammatory responses and nutritional status are useful prognostic factors in gastric cancer patients. Since oral hypofunction causes undernutrition, we cross-sectionally investigated whether nutritional biomarkers were affected by the occlusal supporting zone status. In 114 gastric cancer patients, the gastric cancer stage, body mass index, albumin levels, total lymphocyte counts, cholesterol levels, C-reactive protein levels, and 4 nutritional biomarkers - the Glasgow prognostic score (GPS), neutrophil-lymphocyte ratio, prognostic nutrition index (PNI), and controlling nutritional status (CONUT) - were evaluated. Oral conditions were assessed by determining the number of remaining teeth. The occlusal supporting status was based on the Eichner classification. Patients were assigned into 3 groups per their occlusal status, and mean values were compared using the Kruskal-Wallis test. The mean age and body mass index were 72.2 ± 8.5 (50-89) years and 22.0 ± 3.6 (14.8-33.4), respectively. There were 42, 39, 23, and 10 patients in stages I, II, III, and IV, respectively. The mean number of remaining teeth was 18.1 ± 9.5. According to the Eichner classification, there were 45, 42, and 27 patients in groups A, B, and C, respectively. The GPS and neutrophil-lymphocyte ratio values and CONUT frequencies between groups A and C were significantly different (P = .033, P = .00097, P = .04, respectively; Mann-Whitney U test). PNI values were lower in group C with poor occlusal support zones than in group A with stable occlusal support zones. Occlusal supporting zone reductions were undernutrition associated. Eichner Class C patients with few occlusal supporting zones had poor GPS, PNI, and CONUT values and were undernourished.
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spelling pubmed-106841342023-11-30 Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study Abe, Atsushi Ito, Yu Hayashi, Hiroki Nakayama, Atsushi Furuta, Hiroshi Momokita, Moeko Hasegawa, Hiroaki Tsunoda, Akari Medicine (Baltimore) Observational Study Systemic inflammatory responses and nutritional status are useful prognostic factors in gastric cancer patients. Since oral hypofunction causes undernutrition, we cross-sectionally investigated whether nutritional biomarkers were affected by the occlusal supporting zone status. In 114 gastric cancer patients, the gastric cancer stage, body mass index, albumin levels, total lymphocyte counts, cholesterol levels, C-reactive protein levels, and 4 nutritional biomarkers - the Glasgow prognostic score (GPS), neutrophil-lymphocyte ratio, prognostic nutrition index (PNI), and controlling nutritional status (CONUT) - were evaluated. Oral conditions were assessed by determining the number of remaining teeth. The occlusal supporting status was based on the Eichner classification. Patients were assigned into 3 groups per their occlusal status, and mean values were compared using the Kruskal-Wallis test. The mean age and body mass index were 72.2 ± 8.5 (50-89) years and 22.0 ± 3.6 (14.8-33.4), respectively. There were 42, 39, 23, and 10 patients in stages I, II, III, and IV, respectively. The mean number of remaining teeth was 18.1 ± 9.5. According to the Eichner classification, there were 45, 42, and 27 patients in groups A, B, and C, respectively. The GPS and neutrophil-lymphocyte ratio values and CONUT frequencies between groups A and C were significantly different (P = .033, P = .00097, P = .04, respectively; Mann-Whitney U test). PNI values were lower in group C with poor occlusal support zones than in group A with stable occlusal support zones. Occlusal supporting zone reductions were undernutrition associated. Eichner Class C patients with few occlusal supporting zones had poor GPS, PNI, and CONUT values and were undernourished. Lippincott Williams & Wilkins 2022-03-18 /pmc/articles/PMC10684134/ /pubmed/35356942 http://dx.doi.org/10.1097/MD.0000000000029094 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Observational Study
Abe, Atsushi
Ito, Yu
Hayashi, Hiroki
Nakayama, Atsushi
Furuta, Hiroshi
Momokita, Moeko
Hasegawa, Hiroaki
Tsunoda, Akari
Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study
title Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study
title_full Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study
title_fullStr Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study
title_full_unstemmed Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study
title_short Relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the Eichner index: Observational study
title_sort relationship between nutritional biomarkers and occlusal status in gastric cancer patients using the eichner index: observational study
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684134/
https://www.ncbi.nlm.nih.gov/pubmed/35356942
http://dx.doi.org/10.1097/MD.0000000000029094
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