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Mouse gingival single-cell transcriptomic atlas identified a novel fibroblast subpopulation activated to guide oral barrier immunity in periodontitis

Periodontitis, one of the most common non-communicable diseases, is characterized by chronic oral inflammation and uncontrolled tooth supporting alveolar bone resorption. Its underlying mechanism to initiate aberrant oral barrier immunity has yet to be delineated. Here, we report a unique fibroblast...

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Detalles Bibliográficos
Autores principales: Kondo, Takeru, Gleason, Annie, Okawa, Hiroko, Hokugo, Akishige, Nishimura, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684155/
https://www.ncbi.nlm.nih.gov/pubmed/38015204
http://dx.doi.org/10.7554/eLife.88183