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Mirikizumab-Induced Transcriptome Changes in Ulcerative Colitis Patient Biopsies at Week 12 Are Maintained Through Week 52

INTRODUCTION: Mirikizumab, an anti-interleukin-23p19 monoclonal antibody, demonstrated efficacy in phase 2 and 3 randomized clinical trials of patients with moderate-to-severe ulcerative colitis (UC). Previous results have shown that 12 weeks of mirikizumab treatment downregulated transcripts associ...

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Detalles Bibliográficos
Autores principales:	Johnson, Travis, Steere, Boyd, Zhang, Pengyue, Zang, Yong, Higgs, Richard, Milch, Catherine, Reinisch, Walter, Panés, Julian, Huang, Kun, D'Haens, Geert, Krishnan, Venkatesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684203/ https://www.ncbi.nlm.nih.gov/pubmed/37594044 http://dx.doi.org/10.14309/ctg.0000000000000630

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