Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report

Gut inflammation and defect in the gut mucosal barrier appear to have a correlation with skin diseases and vice versa. The coexistence of hereditary ichthyosis with active colitis has never been reported. We present a 17-year-old female with ichthyosis since birth, abdomen pain for 3 months, with ac...

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Autores principales: Tetarbe, Shivangi, Jain, Suhani, Shah, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins, Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684232/
https://www.ncbi.nlm.nih.gov/pubmed/38034450
http://dx.doi.org/10.1097/PG9.0000000000000370
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author Tetarbe, Shivangi
Jain, Suhani
Shah, Ira
author_facet Tetarbe, Shivangi
Jain, Suhani
Shah, Ira
author_sort Tetarbe, Shivangi
collection PubMed
description Gut inflammation and defect in the gut mucosal barrier appear to have a correlation with skin diseases and vice versa. The coexistence of hereditary ichthyosis with active colitis has never been reported. We present a 17-year-old female with ichthyosis since birth, abdomen pain for 3 months, with acute colitis. After the initial diagnosis, the patient was started on antituberculous therapy (ATT), steroids, and mesalamine. She followed up with us for 1 year where there was resolution of symptoms. Steroids were stopped after 16 weeks, mesalamine was stopped after 20 weeks in view of low absolute neutrophil counts and ATT was stopped after 1 year. She was asymptomatic post 18 months of stopping ATT.
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spelling pubmed-106842322023-11-30 Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report Tetarbe, Shivangi Jain, Suhani Shah, Ira JPGN Rep Case Report Gut inflammation and defect in the gut mucosal barrier appear to have a correlation with skin diseases and vice versa. The coexistence of hereditary ichthyosis with active colitis has never been reported. We present a 17-year-old female with ichthyosis since birth, abdomen pain for 3 months, with acute colitis. After the initial diagnosis, the patient was started on antituberculous therapy (ATT), steroids, and mesalamine. She followed up with us for 1 year where there was resolution of symptoms. Steroids were stopped after 16 weeks, mesalamine was stopped after 20 weeks in view of low absolute neutrophil counts and ATT was stopped after 1 year. She was asymptomatic post 18 months of stopping ATT. Lippincott Williams & Wilkins, Inc. 2023-10-09 /pmc/articles/PMC10684232/ /pubmed/38034450 http://dx.doi.org/10.1097/PG9.0000000000000370 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Tetarbe, Shivangi
Jain, Suhani
Shah, Ira
Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report
title Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report
title_full Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report
title_fullStr Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report
title_full_unstemmed Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report
title_short Hereditary Ichthyosis With Gastrointestinal Manifestations: A Case Report
title_sort hereditary ichthyosis with gastrointestinal manifestations: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684232/
https://www.ncbi.nlm.nih.gov/pubmed/38034450
http://dx.doi.org/10.1097/PG9.0000000000000370
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AT shahira hereditaryichthyosiswithgastrointestinalmanifestationsacasereport

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