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The combination of manogepix and itraconazole is synergistic and inhibits the growth of Madurella mycetomatis in vitro but not in vivo

Mycetoma is a neglected tropical disease commonly caused by the fungus Madurella mycetomatis. Standard treatment consists of extensive treatment with itraconazole in combination with surgical excision of the infected tissue, but has a low success rate. To improve treatment outcomes, novel treatment...

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Detalles Bibliográficos
Autores principales: Konings, Mickey, Eadie, Kimberly, Strepis, Nikolaos, Nyuykonge, Bertrand, Fahal, Ahmed H, Verbon, Annelies, van de Sande, Wendy W J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684268/
https://www.ncbi.nlm.nih.gov/pubmed/37960934
http://dx.doi.org/10.1093/mmy/myad118