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Basket trials in oncology: a systematic review of practices and methods, comparative analysis of innovative methods, and an appraisal of a missed opportunity

BACKGROUND: Basket trials are increasingly used in oncology drug development for early signal detection, accelerated tumor-agnostic approvals, and prioritization of promising tumor types in selected patients with the same mutation or biomarker. Participants are grouped into so-called baskets accordi...

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Detalles Bibliográficos
Autores principales: Kasim, Adetayo, Bean, Nathan, Hendriksen, Sarah Jo, Chen, Tai-Tsang, Zhou, Helen, Psioda, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684308/
https://www.ncbi.nlm.nih.gov/pubmed/38033501
http://dx.doi.org/10.3389/fonc.2023.1266286

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