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COVID-19 mortality and its associated factors in Nepal: A cross-sectional study

OBJECTIVES: Reports from other countries have indicated that severe forms and fatal cases of COVID-19 in older adults and people with underlying comorbidities. The aim of this study was to assess the risk factors associated with COVID-19 mortality in Nepal. METHODS: A cross-sectional study was condu...

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Autores principales: Amatya, Isha, Marasini, Bishnu Prasad, Dhimal, Meghnath, Koirala, Janak, Pokhrel, Nayanum, Gyanwali, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684362/
https://www.ncbi.nlm.nih.gov/pubmed/38035052
http://dx.doi.org/10.1016/j.ijregi.2023.08.002
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author Amatya, Isha
Marasini, Bishnu Prasad
Dhimal, Meghnath
Koirala, Janak
Pokhrel, Nayanum
Gyanwali, Pradip
author_facet Amatya, Isha
Marasini, Bishnu Prasad
Dhimal, Meghnath
Koirala, Janak
Pokhrel, Nayanum
Gyanwali, Pradip
author_sort Amatya, Isha
collection PubMed
description OBJECTIVES: Reports from other countries have indicated that severe forms and fatal cases of COVID-19 in older adults and people with underlying comorbidities. The aim of this study was to assess the risk factors associated with COVID-19 mortality in Nepal. METHODS: A cross-sectional study was conducted from April 12 to July 23, 2021 to identify the underlying factors associated with COVID-19 deaths. Our sample included all cases diagnosed and registered as COVID-19–related deaths at 30 hospitals of Nepal. RESULTS: A total of 1459 COVID-19 hospital-based death records were collected from 30 hospitals. Mean age at death was 60.2 (±15.6) years. One-third of cases were admitted with fever, cough, and shortness of breath. The computerized tomography Severity Score showed that 7.3% of the individuals who underwent high-resolution computerized tomography chest had a severe form of lung involvement, and 3.6% had mild to moderate involvement. The most common comorbidities were hypertension (43.7%) followed by diabetes mellitus (25.8%). Among the deceased, 37.7% were diagnosed as cases of COVID-19 pneumonia. The most common recorded causes of death were respiratory failure followed by cardio-pulmonary arrest. CONCLUSIONS: Individuals with comorbidities including hypertension and diabetes mellitus were at greater risk of developing complications and had a higher rate of mortality.
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spelling pubmed-106843622023-11-30 COVID-19 mortality and its associated factors in Nepal: A cross-sectional study Amatya, Isha Marasini, Bishnu Prasad Dhimal, Meghnath Koirala, Janak Pokhrel, Nayanum Gyanwali, Pradip IJID Reg Original Report OBJECTIVES: Reports from other countries have indicated that severe forms and fatal cases of COVID-19 in older adults and people with underlying comorbidities. The aim of this study was to assess the risk factors associated with COVID-19 mortality in Nepal. METHODS: A cross-sectional study was conducted from April 12 to July 23, 2021 to identify the underlying factors associated with COVID-19 deaths. Our sample included all cases diagnosed and registered as COVID-19–related deaths at 30 hospitals of Nepal. RESULTS: A total of 1459 COVID-19 hospital-based death records were collected from 30 hospitals. Mean age at death was 60.2 (±15.6) years. One-third of cases were admitted with fever, cough, and shortness of breath. The computerized tomography Severity Score showed that 7.3% of the individuals who underwent high-resolution computerized tomography chest had a severe form of lung involvement, and 3.6% had mild to moderate involvement. The most common comorbidities were hypertension (43.7%) followed by diabetes mellitus (25.8%). Among the deceased, 37.7% were diagnosed as cases of COVID-19 pneumonia. The most common recorded causes of death were respiratory failure followed by cardio-pulmonary arrest. CONCLUSIONS: Individuals with comorbidities including hypertension and diabetes mellitus were at greater risk of developing complications and had a higher rate of mortality. Elsevier 2023-09-20 /pmc/articles/PMC10684362/ /pubmed/38035052 http://dx.doi.org/10.1016/j.ijregi.2023.08.002 Text en © 2023 Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Report
Amatya, Isha
Marasini, Bishnu Prasad
Dhimal, Meghnath
Koirala, Janak
Pokhrel, Nayanum
Gyanwali, Pradip
COVID-19 mortality and its associated factors in Nepal: A cross-sectional study
title COVID-19 mortality and its associated factors in Nepal: A cross-sectional study
title_full COVID-19 mortality and its associated factors in Nepal: A cross-sectional study
title_fullStr COVID-19 mortality and its associated factors in Nepal: A cross-sectional study
title_full_unstemmed COVID-19 mortality and its associated factors in Nepal: A cross-sectional study
title_short COVID-19 mortality and its associated factors in Nepal: A cross-sectional study
title_sort covid-19 mortality and its associated factors in nepal: a cross-sectional study
topic Original Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684362/
https://www.ncbi.nlm.nih.gov/pubmed/38035052
http://dx.doi.org/10.1016/j.ijregi.2023.08.002
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