Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies

BACKGROUND AND OBJECTIVES: Isavuconazole is a broad-spectrum antifungal agent for the management of invasive fungal disease. Optimised drug exposure is critical for patient outcomes, specifically in the critically ill population. Solid information on isavuconazole pharmacokinetics including protein...

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Detalles Bibliográficos
Autores principales: Jansen, Anouk M. E., Mertens, Beatrijs, Spriet, Isabel, Verweij, Paul E., Schouten, Jeroen, Wauters, Joost, Debaveye, Yves, ter Heine, Rob, Brüggemann, Roger J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684418/
https://www.ncbi.nlm.nih.gov/pubmed/37819503
http://dx.doi.org/10.1007/s40262-023-01305-8

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