Cargando…
Glibenclamide for Brain Contusions: Contextualizing a Promising Clinical Trial Design that Leverages an Imaging-Based TBI Endotype
TBI heterogeneity is recognized as a major impediment to successful translation of therapies that could improve morbidity and mortality after injury. This heterogeneity exists on multiple levels including primary injury, secondary injury/host-response, and recovery. One widely accepted type of prima...
Autores principales: | Jha, Ruchira M., Simard, J. Marc |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684438/ https://www.ncbi.nlm.nih.gov/pubmed/37306928 http://dx.doi.org/10.1007/s13311-023-01389-x |
Ejemplares similares
-
Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence
por: Jha, Ruchira M., et al.
Publicado: (2020) -
Precision Effects of Glibenclamide on MRI Endophenotypes in Clinically Relevant Murine Traumatic Brain Injury
por: Zusman, Benjamin E., et al.
Publicado: (2022) -
Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study
por: Åkerlund, Cecilia A. I., et al.
Publicado: (2022) -
Glibenclamide for the Treatment of Ischemic and Hemorrhagic Stroke
por: Caffes, Nicholas, et al.
Publicado: (2015) -
Leveraging transcriptomics to develop bronchopulmonary dysplasia endotypes: a concept paper
por: Moreira, Alvaro G., et al.
Publicado: (2023)