Cargando…
The influence of spinal venous blood pressure on cerebrospinal fluid pressure
In Alligator mississippiensis the spinal dura is surrounded by a venous sinus; pressure waves can propagate in the spinal venous blood, and these spinal venous pressures can be transmitted to the spinal cerebrospinal fluid (CSF). This study was designed to explore pressure transfer between the spina...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684553/ https://www.ncbi.nlm.nih.gov/pubmed/38017027 http://dx.doi.org/10.1038/s41598-023-48334-8 |
_version_ | 1785151426676129792 |
---|---|
author | Taylor, Z. English, C. Cramberg, M. Young, B. A. |
author_facet | Taylor, Z. English, C. Cramberg, M. Young, B. A. |
author_sort | Taylor, Z. |
collection | PubMed |
description | In Alligator mississippiensis the spinal dura is surrounded by a venous sinus; pressure waves can propagate in the spinal venous blood, and these spinal venous pressures can be transmitted to the spinal cerebrospinal fluid (CSF). This study was designed to explore pressure transfer between the spinal venous blood and the spinal CSF. At rest the cardiac-related CSF pulsations are attenuated and delayed, while the ventilatory-related pulsations are amplified as they move from the spinal venous blood to the spinal CSF. Orthostatic gradients resulted in significant alterations of both cardiac- and ventilatory-related CSF pulsations. Manual lateral oscillations of the alligator’s tail created pressure waves in the spinal CSF that propagated, with slight attenuation but no delay, to the cranial CSF. Oscillatory pressure pulsations in the spinal CSF and venous blood had little influence on the underlying ventilatory pulsations, though the same oscillatory pulsations reduced the ventilatory- and increased the cardiac-related pulsations in the cranial CSF. In Alligator the spinal venous anatomy creates a more complex pressure relationship between the venous and CSF systems than has been described in humans. |
format | Online Article Text |
id | pubmed-10684553 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-106845532023-11-30 The influence of spinal venous blood pressure on cerebrospinal fluid pressure Taylor, Z. English, C. Cramberg, M. Young, B. A. Sci Rep Article In Alligator mississippiensis the spinal dura is surrounded by a venous sinus; pressure waves can propagate in the spinal venous blood, and these spinal venous pressures can be transmitted to the spinal cerebrospinal fluid (CSF). This study was designed to explore pressure transfer between the spinal venous blood and the spinal CSF. At rest the cardiac-related CSF pulsations are attenuated and delayed, while the ventilatory-related pulsations are amplified as they move from the spinal venous blood to the spinal CSF. Orthostatic gradients resulted in significant alterations of both cardiac- and ventilatory-related CSF pulsations. Manual lateral oscillations of the alligator’s tail created pressure waves in the spinal CSF that propagated, with slight attenuation but no delay, to the cranial CSF. Oscillatory pressure pulsations in the spinal CSF and venous blood had little influence on the underlying ventilatory pulsations, though the same oscillatory pulsations reduced the ventilatory- and increased the cardiac-related pulsations in the cranial CSF. In Alligator the spinal venous anatomy creates a more complex pressure relationship between the venous and CSF systems than has been described in humans. Nature Publishing Group UK 2023-11-28 /pmc/articles/PMC10684553/ /pubmed/38017027 http://dx.doi.org/10.1038/s41598-023-48334-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Taylor, Z. English, C. Cramberg, M. Young, B. A. The influence of spinal venous blood pressure on cerebrospinal fluid pressure |
title | The influence of spinal venous blood pressure on cerebrospinal fluid pressure |
title_full | The influence of spinal venous blood pressure on cerebrospinal fluid pressure |
title_fullStr | The influence of spinal venous blood pressure on cerebrospinal fluid pressure |
title_full_unstemmed | The influence of spinal venous blood pressure on cerebrospinal fluid pressure |
title_short | The influence of spinal venous blood pressure on cerebrospinal fluid pressure |
title_sort | influence of spinal venous blood pressure on cerebrospinal fluid pressure |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684553/ https://www.ncbi.nlm.nih.gov/pubmed/38017027 http://dx.doi.org/10.1038/s41598-023-48334-8 |
work_keys_str_mv | AT taylorz theinfluenceofspinalvenousbloodpressureoncerebrospinalfluidpressure AT englishc theinfluenceofspinalvenousbloodpressureoncerebrospinalfluidpressure AT crambergm theinfluenceofspinalvenousbloodpressureoncerebrospinalfluidpressure AT youngba theinfluenceofspinalvenousbloodpressureoncerebrospinalfluidpressure AT taylorz influenceofspinalvenousbloodpressureoncerebrospinalfluidpressure AT englishc influenceofspinalvenousbloodpressureoncerebrospinalfluidpressure AT crambergm influenceofspinalvenousbloodpressureoncerebrospinalfluidpressure AT youngba influenceofspinalvenousbloodpressureoncerebrospinalfluidpressure |