Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2

In Alzheimer’s disease (AD) more than 50% of the patients are affected by capillary cerebral amyloid-angiopathy (capCAA), which is characterized by localized hypoxia, neuro-inflammation and loss of blood-brain barrier (BBB) function. Moreover, AD patients with or without capCAA display increased ves...

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Detalles Bibliográficos
Autores principales: Vacondio, D., Nogueira Pinto, H., Coenen, L., Mulder, I. A., Fontijn, R., van het Hof, B., Fung, W. K., Jongejan, A., Kooij, G., Zelcer, N., Rozemuller, A. J., de Vries, H. E., de Wit, N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684660/
https://www.ncbi.nlm.nih.gov/pubmed/38016947
http://dx.doi.org/10.1038/s41419-023-06316-8

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