Reactivation of telomerase reverse transcriptase expression in cancer: the role of TERT promoter mutations

Telomerase activity and telomere elongation are essential conditions for the unlimited proliferation of neoplastic cells. Point mutations in the core promoter region of the telomerase reverse transcriptase (TERT) gene have been found to occur at high frequencies in several tumour types and considere...

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Detalles Bibliográficos
Autores principales: Tornesello, Maria Lina, Cerasuolo, Andrea, Starita, Noemy, Amiranda, Sara, Bonelli, Patrizia, Tuccillo, Franca Maria, Buonaguro, Franco M., Buonaguro, Luigi, Tornesello, Anna Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684755/
https://www.ncbi.nlm.nih.gov/pubmed/38033865
http://dx.doi.org/10.3389/fcell.2023.1286683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10684755/
https://www.ncbi.nlm.nih.gov/pubmed/38033865
http://dx.doi.org/10.3389/fcell.2023.1286683

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